TY - JOUR
T1 - Comparison of Immediate Neuromodulatory Effects between Focal Vibratory and Electrical Sensory Stimulations after Stroke
AU - Lin, Legeng
AU - Qing, Wanyi
AU - Huang, Yanhuan
AU - Ye, Fuqiang
AU - Rong, Wei
AU - Li, Waiming
AU - Jiao, Jiao
AU - Hu, Xiaoling
N1 - Funding information:
This research was funded by the University Grants Committee Research Grants Council, Hong Kong (GRF15207120); The Hong Kong Polytechnic University (1-ZVVP and 1-CD74); and Innovation and Technology Fund (ITT/012/23GP).
Publisher copyright:
© 2024 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2024/3
Y1 - 2024/3
N2 - Focal vibratory stimulation (FVS) and neuromuscular electrical stimulation (NMES) are promising technologies for sensory rehabilitation after stroke. However, the differences between these techniques in immediate neuromodulatory effects on the poststroke cortex are not yet fully understood. In this research, cortical responses in persons with chronic stroke (n = 15) and unimpaired controls (n = 15) were measured by whole-brain electroencephalography (EEG) when FVS and NMES at different intensities were applied transcutaneously to the forearm muscles. Both FVS and sensory-level NMES induced alpha and beta oscillations in the sensorimotor cortex after stroke, significantly exceeding baseline levels (p < 0.05). These oscillations exhibited bilateral sensory deficiency, early adaptation, and contralesional compensation compared to the control group. FVS resulted in a significantly faster P300 response (p < 0.05) and higher theta oscillation (p < 0.05) compared to NMES. The beta desynchronization over the contralesional frontal-parietal area remained during NMES (p > 0.05), but it was significantly weakened during FVS (p < 0.05) after stroke. The results indicated that both FVS and NMES effectively activated the sensorimotor cortex after stroke. However, FVS was particularly effective in eliciting transient involuntary attention, while NMES primarily fostered the cortical responses of the targeted muscles in the contralesional motor cortex.
AB - Focal vibratory stimulation (FVS) and neuromuscular electrical stimulation (NMES) are promising technologies for sensory rehabilitation after stroke. However, the differences between these techniques in immediate neuromodulatory effects on the poststroke cortex are not yet fully understood. In this research, cortical responses in persons with chronic stroke (n = 15) and unimpaired controls (n = 15) were measured by whole-brain electroencephalography (EEG) when FVS and NMES at different intensities were applied transcutaneously to the forearm muscles. Both FVS and sensory-level NMES induced alpha and beta oscillations in the sensorimotor cortex after stroke, significantly exceeding baseline levels (p < 0.05). These oscillations exhibited bilateral sensory deficiency, early adaptation, and contralesional compensation compared to the control group. FVS resulted in a significantly faster P300 response (p < 0.05) and higher theta oscillation (p < 0.05) compared to NMES. The beta desynchronization over the contralesional frontal-parietal area remained during NMES (p > 0.05), but it was significantly weakened during FVS (p < 0.05) after stroke. The results indicated that both FVS and NMES effectively activated the sensorimotor cortex after stroke. However, FVS was particularly effective in eliciting transient involuntary attention, while NMES primarily fostered the cortical responses of the targeted muscles in the contralesional motor cortex.
KW - cortical response
KW - electroencephalography (EEG)
KW - focal vibratory stimulation (FVS)
KW - neuromodulation
KW - neuromuscular electrical stimulation (NMES)
KW - somatosensory impairment
KW - stroke
UR - http://www.scopus.com/inward/record.url?scp=85188685002&partnerID=8YFLogxK
U2 - 10.3390/bioengineering11030286
DO - 10.3390/bioengineering11030286
M3 - Journal article
C2 - 38534560
SN - 2306-5354
VL - 11
JO - Bioengineering
JF - Bioengineering
IS - 3
M1 - 286
ER -
