Comparative Metabolomics Combined with Physiological Analysis Revealed Cadmium Tolerance Mechanism in Indica Rice (Oryza sativa L.)

Weixia Chang, Wei Wang, Zhangsheng Shi, Guodong Cao, Xingchen Zhao, Xiuli Su, Yi Chen, Jiabin Wu, Zhu Yang, Chaolei Liu, Lianguang Shang*, Zongwei Cai*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

5 Citations (Scopus)

Abstract

Cadmium (Cd) pollution reduces rice production and quality, putting food security and human health at risk. We conducted comparative physiology and metabolomic analyses in two indica rice (‘NH199’ and ‘NH224’) to elucidate the Cd-tolerance mechanism. Cd hampered rice growth, induced oxidative stress, and changed the metabolomics profiling of the root. The biochemical and physiological analysis demonstrated that NH224 exhibited a more potent Cd-tolerance ability than NH199. Cd was primarily distributed in root, and NH224 had a lower Cd translocation factor than NH199 by about 24%. The metabolomic analysis revealed 180 and 177 differentially accumulated metabolites between Cd-stressed seedlings and the controls in NH224 and NH199, respectively. In NH224, amino acids biosynthesis, hormone metabolism, lipids-related metabolism, phenylalanine metabolism, and phenylpropanoid biosynthesis pathways were more active and highly associated with antioxidant defense system, biosynthesis of the cell wall and phytochelatins, and maintenance of plasma membrane stability. These findings provide insights into the metabolic profiles of rice following Cd stress and the screening and breeding of Cd-tolerant rice varieties.

Original languageEnglish
Pages (from-to)7669-7678
Number of pages10
JournalJournal of Agricultural and Food Chemistry
Volume71
Issue number20
Early online date9 May 2023
DOIs
Publication statusPublished - 24 May 2023

Scopus Subject Areas

  • Agricultural and Biological Sciences(all)
  • Chemistry(all)

User-Defined Keywords

  • cadmium stress
  • metabolomics
  • physiology
  • rice
  • tolerant genotype

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