Combining functional and linkage disequilibrium information in the selection of tag SNPs

P. C. Sham*, S. I. Ao, J. S.H. Kwan, P. Kao, F. Cheung, P. Y. Fong, Kwok Po NG

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

Summary: We have developed an online program, WCLUSTAG, for tag SNP selection that allows the user to specify variable tagging thresholds for different SNPs. Tag SNPs are selected such that a SNP with user-specified tagging threshold C will have a minimum R2 of C with at least one tag SNP. This flexible feature is useful for researchers who wish to prioritize genomic regions or SNPs in an association study.

Original languageEnglish
Pages (from-to)129-131
Number of pages3
JournalBioinformatics
Volume23
Issue number1
DOIs
Publication statusPublished - Jan 2007

Scopus Subject Areas

  • Statistics and Probability
  • Biochemistry
  • Molecular Biology
  • Computer Science Applications
  • Computational Theory and Mathematics
  • Computational Mathematics

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