Keyphrases
Protein Degradation
100%
Ubiquitin-proteasome System
100%
Combination Treatment
100%
Artesunate
100%
E3 Ligase
100%
WNT974
100%
KRAS Protein
100%
Glycogen Synthase Kinase 3 (GSK3)
83%
Protein Level
50%
Colorectal Cancer
50%
Mammalian Target of Rapamycin (mTOR)
50%
Synergistic Effect
33%
Knockdown
33%
Ubiquitination
33%
AKT1
33%
Colorectal Cancer Cells
33%
Xenograft Mouse Model
33%
Phosphoinositide 3-kinase (PI3K)
33%
Colorectal Cancer Prevention
33%
Water-soluble
16%
MRNA Level
16%
Quantitative PCR
16%
Overexpression
16%
Tumor Tissue
16%
MTT Assay
16%
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium Bromide
16%
Cancer Growth
16%
Synthetic Derivatives
16%
Artemisinin
16%
Protein Activity
16%
KRAS mutation
16%
Wnt Signaling Pathway
16%
Targeted Therapeutics
16%
Western Blot Assay
16%
Cancer Cell Viability
16%
MG132
16%
Cancer Effects
16%
Anti-colorectal Cancer
16%
Porcupine Inhibitor
16%
Gene mutation
16%
CUL7
16%
UBE2M
16%
RNF123
16%
LGK974
16%
IHC Assay
16%
SYVN1
16%
Dominant Gene
16%
TOR Signaling Pathway
16%
Pharmacology, Toxicology and Pharmaceutical Science
Colorectal Carcinoma
100%
Artesunate
100%
Ligase
100%
Glycogen Synthase Kinase
62%
Protein Kinase B
37%
Mouse Model
25%
Messenger RNA
12%
Western Blot
12%
Neoplasm
12%
Cell Viability
12%
3 (4,5 Dimethyl 2 Thiazolyl) 2,5 Diphenyltetrazolium Bromide
12%
Cancer Growth
12%
Artemisinin
12%
Porcupine
12%
Benzyloxycarbonylleucylleucylleucinal
12%