Cholic acid-based fluorescent sensor for mercuric and methyl mercuric ion in aqueous solutions

Hao Wang, Wing Hong CHAN*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

38 Citations (Scopus)

Abstract

Cholic acid-based fluorescent PET sensor probe 1, bearing a pair of dithiocarbamate pendants as the receptive site and anthracene moiety as the signal displaying unit, was designed and synthesized. The sensor probe not only shows high selectivity and sensitivity to Hg2+ in aqueous acetonitrile solution, but also responds moderately to MeHg+. A distinctive OFF-ON type signaling of up to 10-fold enhancement was observed for this new sensor probe toward Hg2+.

Original languageEnglish
Pages (from-to)8825-8830
Number of pages6
JournalTetrahedron
Volume63
Issue number36
DOIs
Publication statusPublished - 3 Sep 2007

Scopus Subject Areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

User-Defined Keywords

  • Cholic acid
  • Fluorescence
  • Mercury chemosensor
  • OFF-ON type signaling

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