Cholic acid-based fluorescent sensor for mercuric and methyl mercuric ion in aqueous solutions

Hao Wang; Wing Hong CHAN

doi:10.1016/j.tet.2007.06.026

Cholic acid-based fluorescent sensor for mercuric and methyl mercuric ion in aqueous solutions

Hao Wang, Wing Hong CHAN^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

40 Citations (Scopus)

Abstract

Cholic acid-based fluorescent PET sensor probe 1, bearing a pair of dithiocarbamate pendants as the receptive site and anthracene moiety as the signal displaying unit, was designed and synthesized. The sensor probe not only shows high selectivity and sensitivity to Hg²⁺ in aqueous acetonitrile solution, but also responds moderately to MeHg⁺. A distinctive OFF-ON type signaling of up to 10-fold enhancement was observed for this new sensor probe toward Hg²⁺.

Original language	English
Pages (from-to)	8825-8830
Number of pages	6
Journal	Tetrahedron
Volume	63
Issue number	36
DOIs	https://doi.org/10.1016/j.tet.2007.06.026
Publication status	Published - 3 Sept 2007

Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

User-Defined Keywords

Cholic acid
Fluorescence
Mercury chemosensor
OFF-ON type signaling

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10.1016/j.tet.2007.06.026

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title = "Cholic acid-based fluorescent sensor for mercuric and methyl mercuric ion in aqueous solutions",

abstract = "Cholic acid-based fluorescent PET sensor probe 1, bearing a pair of dithiocarbamate pendants as the receptive site and anthracene moiety as the signal displaying unit, was designed and synthesized. The sensor probe not only shows high selectivity and sensitivity to Hg2+ in aqueous acetonitrile solution, but also responds moderately to MeHg+. A distinctive OFF-ON type signaling of up to 10-fold enhancement was observed for this new sensor probe toward Hg2+.",

keywords = "Cholic acid, Fluorescence, Mercury chemosensor, OFF-ON type signaling",

author = "Hao Wang and CHAN, {Wing Hong}",

note = "Funding Information: A marginally funded studentship provided by the UGC of Hong Kong to H.W. and financial support from the Science Faculty of Hong Kong Baptist University are acknowledged. ",

year = "2007",

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doi = "10.1016/j.tet.2007.06.026",

language = "English",

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journal = "Tetrahedron",

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TY - JOUR

T1 - Cholic acid-based fluorescent sensor for mercuric and methyl mercuric ion in aqueous solutions

AU - Wang, Hao

AU - CHAN, Wing Hong

N1 - Funding Information: A marginally funded studentship provided by the UGC of Hong Kong to H.W. and financial support from the Science Faculty of Hong Kong Baptist University are acknowledged.

PY - 2007/9/3

Y1 - 2007/9/3

N2 - Cholic acid-based fluorescent PET sensor probe 1, bearing a pair of dithiocarbamate pendants as the receptive site and anthracene moiety as the signal displaying unit, was designed and synthesized. The sensor probe not only shows high selectivity and sensitivity to Hg2+ in aqueous acetonitrile solution, but also responds moderately to MeHg+. A distinctive OFF-ON type signaling of up to 10-fold enhancement was observed for this new sensor probe toward Hg2+.

AB - Cholic acid-based fluorescent PET sensor probe 1, bearing a pair of dithiocarbamate pendants as the receptive site and anthracene moiety as the signal displaying unit, was designed and synthesized. The sensor probe not only shows high selectivity and sensitivity to Hg2+ in aqueous acetonitrile solution, but also responds moderately to MeHg+. A distinctive OFF-ON type signaling of up to 10-fold enhancement was observed for this new sensor probe toward Hg2+.

KW - Cholic acid

KW - Fluorescence

KW - Mercury chemosensor

KW - OFF-ON type signaling

UR - http://www.scopus.com/inward/record.url?scp=34447624712&partnerID=8YFLogxK

U2 - 10.1016/j.tet.2007.06.026

DO - 10.1016/j.tet.2007.06.026

M3 - Journal article

AN - SCOPUS:34447624712

SN - 0040-4020

VL - 63

SP - 8825

EP - 8830

JO - Tetrahedron

JF - Tetrahedron

IS - 36

ER -

Cholic acid-based fluorescent sensor for mercuric and methyl mercuric ion in aqueous solutions

Abstract

Scopus Subject Areas

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