Cholic-acid-based fluorescent sensor for dicarboxylates and acidic amino acids in aqueous solutions

Shun Ying Liu, Lei Fang, Yong Bing He, Wing Hong CHAN*, Kai Tai Yeung, Yuen Kit CHENG, Rong Hua Yang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

122 Citations (Scopus)

Abstract

(Figure Presented) The binding affinities of a cholic-acid-based fluorescent neutral receptor toward dicarboxylate anions and amino acids have been investigated in a CH3OH/H2O system (1:1, 0.01 M HEPES buffer, pH = 7.4) by fluorescence titration experiments. The synthetic host bearing four convergent functionalities strongly binds glutamate via multiple hydrogen bonds with a binding constant of (5.57 ± 0.88) × 10 6.

Original languageEnglish
Pages (from-to)5825-5828
Number of pages4
JournalOrganic Letters
Volume7
Issue number26
DOIs
Publication statusPublished - 22 Dec 2005

Scopus Subject Areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Cholic-acid-based fluorescent sensor for dicarboxylates and acidic amino acids in aqueous solutions'. Together they form a unique fingerprint.

Cite this