Chiral acetylenic sulfoxide in enantioselective synthesis of yohimbine alkaloid

Albert W M LEE*, Wing Hong CHAN, T. Mo

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

17 Citations (Scopus)

Abstract

Through Michael addition/acid induced cyclization of secondary amine to chiral acetylenic sulfoxide followed by Pummerer cyclization, an approach to the enantioselective syntheses of pentacyclic yohimbine alkaloids is presented.

Original languageEnglish
Pages (from-to)3001-3004
Number of pages4
JournalTetrahedron Letters
Volume38
Issue number17
DOIs
Publication statusPublished - 28 Apr 1997

Scopus Subject Areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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