Chemoselective reduction of aldehydes: Via a combination of NaBH4 and acetylacetone

  • Guoqing Sui
  • , Qingyun Lv
  • , Xiaoqing Song
  • , Huihui Guo
  • , Jiatong Dai
  • , Li Ren
  • , Chi Sing Lee
  • , Wenming Zhou*
  • , Hong Dong Hao
  • *Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

4 Citations (Scopus)

Abstract

A bench-stable combination of NaBH4-acetylacetone was developed for the efficient chemoselective reduction of aldehydes in the presence of ketones. This method offers a useful synthetic protocol for distinguishing carbonyl reaction sites, and its synthetic utility is reflected by its moisture tolerance and high efficiency in a variety of complex settings.

Original languageEnglish
Pages (from-to)15793-15796
Number of pages4
JournalNew Journal of Chemistry
Volume43
Issue number39
Early online date9 Sept 2019
DOIs
Publication statusPublished - 21 Oct 2019

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