Chemoselective reduction of aldehydes: Via a combination of NaBH4 and acetylacetone

Guoqing Sui, Qingyun Lv, Xiaoqing Song, Huihui Guo, Jiatong Dai, Li Ren, Chi Sing Lee, Wenming Zhou*, Hong Dong Hao

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review


A bench-stable combination of NaBH4-acetylacetone was developed for the efficient chemoselective reduction of aldehydes in the presence of ketones. This method offers a useful synthetic protocol for distinguishing carbonyl reaction sites, and its synthetic utility is reflected by its moisture tolerance and high efficiency in a variety of complex settings.

Original languageEnglish
Pages (from-to)15793-15796
Number of pages4
JournalNew Journal of Chemistry
Issue number39
Early online date9 Sept 2019
Publication statusPublished - 21 Oct 2019

Scopus Subject Areas

  • Catalysis
  • Chemistry(all)
  • Materials Chemistry


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