@article{ed983b4f86fd42eea00c77397ca44b77,
title = "Chemoselective detection of alkyl halides via an iridium(III) luminescent probe",
abstract = "The high reactivity of alkyl halides towards nucleophiles renders them as acutely toxic and mutagenic agents. Therefore, it is urgent to develop simple, sensitive, and selective methods for the detection of alkylating agents in a wide range of scenarios. Herein, we have designed and synthesized a novel cyclometalated iridium(III) complex Ir_1 as a rapid and effective chemosensor for a range of alkyl halides based on cycloaddition reaction. Ir_1 displayed an enhanced luminescence with the increase of BnBr-thiourea concentration, within a linear range of 0.8–8 μM BnBr-thiourea, and the detection limit at a signal-to-noise ratio of 3 was as low as 0.39 μM.",
keywords = "Alkyl halides, Chemosensor, Iridium",
author = "Chun Wu and Liu, {Jin Biao} and Guodong Li and Wong, {Suk Yu} and Han, {Simon Q B} and Leung, {Chung Hang} and Ma, {Edmond Dik Lung}",
note = "Funding Information: This work is supported by Hong Kong Baptist University (FRG2/16-17/007 and FRG2/17-18/003), the Health and Medical Research Fund (HMRF/14150561), the Research Grants Council (HKBU/12301115), the National Natural Science Foundation of China (21575121, 21775131, 21628502, 21502075 and 21762018), the Guangdong Province Natural Science Foundation (2015A030313816), the Hong Kong Baptist University Century Club Sponsorship Scheme 2017, the Interdisciplinary Research Matching Scheme (RC-IRMS/15-16/03 and RC-IRMS/16-17/03), Innovation and Technology Fund (ITS/260/16FX), Collaborative Research Fund (C5026-16G), Matching Proof of Concept Fund (MPCF-001-2017/18), the Science and Technology Development Fund, Macao SAR (077/2016/A2), the University of Macau (MYRG2016-00151-ICMS-QRCM), and the Natural Science Foundation of Jiangxi Province (20171BAB213008). Funding Information: This work is supported by Hong Kong Baptist University ( FRG2/16-17/007 and FRG2/17-18/003 ), the Health and Medical Research Fund ( HMRF/14150561 ), the Research Grants Council ( HKBU/12301115 ), the National Natural Science Foundation of China ( 21575121 , 21775131 , 21628502 , 21502075 and 21762018 ), the Guangdong Province Natural Science Foundation ( 2015A030313816 ), the Hong Kong Baptist University Century Club Sponsorship Scheme 2017, the Interdisciplinary Research Matching Scheme ( RC-IRMS/15-16/03 and RC-IRMS/16-17/03 ), Innovation and Technology Fund ( ITS/260/16FX ), Collaborative Research Fund ( C5026-16G ), Matching Proof of Concept Fund ( MPCF-001-2017/18 ), the Science and Technology Development Fund , Macao SAR ( 077/2016/A2 ), the University of Macau ( MYRG2016-00151-ICMS-QRCM ), and the Natural Science Foundation of Jiangxi Province ( 20171BAB213008 ). ",
year = "2018",
month = dec,
doi = "10.1016/j.dyepig.2018.07.029",
language = "English",
volume = "159",
pages = "479--482",
journal = "Dyes and Pigments",
issn = "0143-7208",
publisher = "Elsevier BV",
}