Chemical constituents from Xylosma longifolia and their anti-tubercular activity

Bich Ngan Truong, Van Cuong Pham*, Huong Doan Thi Mai, Van Hung Nguyen, Manh Cuong Nguyen, Hiêp Tien Nguyen, Hong Jie Zhang, Harry H.S. Fong, Scott G. Franzblau, Djaja D. Soejarto, Van Minh Chau*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

9 Citations (Scopus)

Abstract

Two new glucosides, 3-methoxy-4-hydroxyphenylpropane-7,8-(6′-benzoyl- 2′,1′-O-β-glucopyranosyl)-7,8,9-trio (1), and 2-hydroxyphenyl-4-caffeoyl-β-d-glucoside (2), together with seven known compounds were isolated from the stem bark of Xylosma longifolia (Flacourtiaceae). The structures of the isolates were established on the basis of their spectral data, including mass spectrometry and 2D-NMR. The compound 8-hydroxy-6-methoxy-pentylisocoumarin (3) exhibited an MIC value of 40.5 μg/mL against M. tuberculosis.

Original languageEnglish
Pages (from-to)250-253
Number of pages4
JournalPhytochemistry Letters
Volume4
Issue number3
DOIs
Publication statusPublished - Sept 2011

Scopus Subject Areas

  • Biotechnology
  • Biochemistry
  • Agronomy and Crop Science
  • Plant Science

User-Defined Keywords

  • 8-Hydroxy-6-methoxy- pentylisocoumarin
  • Anti-tuberculosis
  • Flacourtiaceae
  • Xylongoside
  • Xylosma longifolia

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