Chemical and biological characterization of air particulate matter 2.5, collected from five cities in China

P. Y. Leung; H. T. Wan; M. B. Billah; J. J. Cao; K. F. Ho; Chris K.C. Wong

doi:10.1016/j.envpol.2014.07.032

Chemical and biological characterization of air particulate matter 2.5, collected from five cities in China

P. Y. Leung
, H. T. Wan
, M. B. Billah
, J. J. Cao
, K. F. Ho
, Chris K.C. Wong^*

^*Corresponding author for this work

Department of Biology

Research output: Contribution to journal › Journal article › peer-review

58 Citations (Scopus)

Abstract

Fifteen polycyclic aromatic hydrocarbons (PAHs) in PM_2.5 samples collected in five different cities (Hong Kong (HK), Guangzhou (GZ), Xiamen (XM), Xi'an (XA) and Beijing (BJ)) in China in the winter 2012-12 were analyzed by gas chromatography-mass spectrometry. The biological effects of organic extracts were assayed using the human bronchial epithelial cells BEAS-2B. All sixteen priority PAHs can be found in the PM_2.5 samples of XA and BJ, but not in HK, GZ and XM, demonstrating the differential spatial source and distribution of PAHs. Our results showed that the total PAHs ranged from 3.35 to 80.45 ng/m³ air, leading by BJ, followed by XA, XM, GZ and HK. In the cell culture study, transcript levels of pro-inflammatory cytokine interleukin-6 (IL-6), CYP1A1 and CYP1B1 were found to be induced in the treatment. The cells exposed to extracts from XA and BJ demonstrated significant migratory activities, indicating a sign of increase of tumorigenicity.

Original language	English
Pages (from-to)	188-195
Number of pages	8
Journal	Environmental Pollution
Volume	194
DOIs	https://doi.org/10.1016/j.envpol.2014.07.032
Publication status	Published - Nov 2014

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 11 Sustainable Cities and Communities

User-Defined Keywords

Polycyclic aromatic hydrocarbons
TEF
Tumorigenicity

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10.1016/j.envpol.2014.07.032

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@article{f7491d0e50014cc9b36dd0009d3747b2,

title = "Chemical and biological characterization of air particulate matter 2.5, collected from five cities in China",

abstract = "Fifteen polycyclic aromatic hydrocarbons (PAHs) in PM2.5 samples collected in five different cities (Hong Kong (HK), Guangzhou (GZ), Xiamen (XM), Xi'an (XA) and Beijing (BJ)) in China in the winter 2012-12 were analyzed by gas chromatography-mass spectrometry. The biological effects of organic extracts were assayed using the human bronchial epithelial cells BEAS-2B. All sixteen priority PAHs can be found in the PM2.5 samples of XA and BJ, but not in HK, GZ and XM, demonstrating the differential spatial source and distribution of PAHs. Our results showed that the total PAHs ranged from 3.35 to 80.45 ng/m3 air, leading by BJ, followed by XA, XM, GZ and HK. In the cell culture study, transcript levels of pro-inflammatory cytokine interleukin-6 (IL-6), CYP1A1 and CYP1B1 were found to be induced in the treatment. The cells exposed to extracts from XA and BJ demonstrated significant migratory activities, indicating a sign of increase of tumorigenicity.",

keywords = "Polycyclic aromatic hydrocarbons, TEF, Tumorigenicity",

author = "Leung, \{P. Y.\} and Wan, \{H. T.\} and Billah, \{M. B.\} and Cao, \{J. J.\} and Ho, \{K. F.\} and Wong, \{Chris K.C.\}",

note = "Funding Information: This work was supported by the Strategy Development Fund, Hong Kong Baptist University (CKC Wong).",

year = "2014",

month = nov,

doi = "10.1016/j.envpol.2014.07.032",

language = "English",

volume = "194",

pages = "188--195",

journal = "Environmental Pollution",

issn = "0269-7491",

publisher = "Elsevier Ltd.",

}

TY - JOUR

T1 - Chemical and biological characterization of air particulate matter 2.5, collected from five cities in China

AU - Leung, P. Y.

AU - Wan, H. T.

AU - Billah, M. B.

AU - Cao, J. J.

AU - Ho, K. F.

AU - Wong, Chris K.C.

N1 - Funding Information: This work was supported by the Strategy Development Fund, Hong Kong Baptist University (CKC Wong).

PY - 2014/11

Y1 - 2014/11

N2 - Fifteen polycyclic aromatic hydrocarbons (PAHs) in PM2.5 samples collected in five different cities (Hong Kong (HK), Guangzhou (GZ), Xiamen (XM), Xi'an (XA) and Beijing (BJ)) in China in the winter 2012-12 were analyzed by gas chromatography-mass spectrometry. The biological effects of organic extracts were assayed using the human bronchial epithelial cells BEAS-2B. All sixteen priority PAHs can be found in the PM2.5 samples of XA and BJ, but not in HK, GZ and XM, demonstrating the differential spatial source and distribution of PAHs. Our results showed that the total PAHs ranged from 3.35 to 80.45 ng/m3 air, leading by BJ, followed by XA, XM, GZ and HK. In the cell culture study, transcript levels of pro-inflammatory cytokine interleukin-6 (IL-6), CYP1A1 and CYP1B1 were found to be induced in the treatment. The cells exposed to extracts from XA and BJ demonstrated significant migratory activities, indicating a sign of increase of tumorigenicity.

AB - Fifteen polycyclic aromatic hydrocarbons (PAHs) in PM2.5 samples collected in five different cities (Hong Kong (HK), Guangzhou (GZ), Xiamen (XM), Xi'an (XA) and Beijing (BJ)) in China in the winter 2012-12 were analyzed by gas chromatography-mass spectrometry. The biological effects of organic extracts were assayed using the human bronchial epithelial cells BEAS-2B. All sixteen priority PAHs can be found in the PM2.5 samples of XA and BJ, but not in HK, GZ and XM, demonstrating the differential spatial source and distribution of PAHs. Our results showed that the total PAHs ranged from 3.35 to 80.45 ng/m3 air, leading by BJ, followed by XA, XM, GZ and HK. In the cell culture study, transcript levels of pro-inflammatory cytokine interleukin-6 (IL-6), CYP1A1 and CYP1B1 were found to be induced in the treatment. The cells exposed to extracts from XA and BJ demonstrated significant migratory activities, indicating a sign of increase of tumorigenicity.

KW - Polycyclic aromatic hydrocarbons

KW - TEF

KW - Tumorigenicity

UR - https://www.scopus.com/pages/publications/84906509320

UR - https://www.sciencedirect.com/science/article/pii/S0269749114003881?via%3Dihub

U2 - 10.1016/j.envpol.2014.07.032

DO - 10.1016/j.envpol.2014.07.032

M3 - Journal article

C2 - 25150452

AN - SCOPUS:84906509320

SN - 0269-7491

VL - 194

SP - 188

EP - 195

JO - Environmental Pollution

JF - Environmental Pollution

ER -

Chemical and biological characterization of air particulate matter 2.5, collected from five cities in China

Abstract

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