TY - JOUR
T1 - Chemical and bioanalytical characterization of dioxins in indoor dust in Hong Kong
AU - Kang, Yuan
AU - Cheung, Kwai Chung
AU - CAI, Zongwei
AU - WONG, Ming Hung
N1 - Funding Information:
Financial support from the Research Grants Council of the University Grants Committee of Hong Kong ( HKBU 260209 ) and Special Equipment Grant ( HKBU09 ) and the Mini-AoE (Area of Excellence, RC/AOE/08-09/01) Fund from Hong Kong Baptist University are gratefully acknowledged.
PY - 2011/5
Y1 - 2011/5
N2 - In the present work, air-conditioner filter dust samples collected from commercial office, secondary school, shopping mall, electronic factory and manufacturing plant in Hong Kong were collected for 7-ethoxyresorufin O-deethylase (EROD) assay using a hepatoma cell line (H4IIE) and chemical analysis of dioxins including polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and PCBs with dioxin-like structure. The result of EROD assay showed that bioassay derived TEQ of 2,3,7,8-TCDD (TEQbio) of dust samples varied from 320 to 730pg/g. Chemical analyses revealed that chemical derived TEQ of 2,3,7,8-TCDD (TEQcal) of dust samples ranged from 134 to 531pg/g. In addition, the TEQcal of samples were significantly correlated with TEQbio of samples (R=0.83, P<0.01). The average daily doses (ADDs) of dioxins via indoor dust with the estimated ADDs of dioxins via air and food were compared. The results showed that indoor dust is an important medium of exposure to dioxins.
AB - In the present work, air-conditioner filter dust samples collected from commercial office, secondary school, shopping mall, electronic factory and manufacturing plant in Hong Kong were collected for 7-ethoxyresorufin O-deethylase (EROD) assay using a hepatoma cell line (H4IIE) and chemical analysis of dioxins including polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and PCBs with dioxin-like structure. The result of EROD assay showed that bioassay derived TEQ of 2,3,7,8-TCDD (TEQbio) of dust samples varied from 320 to 730pg/g. Chemical analyses revealed that chemical derived TEQ of 2,3,7,8-TCDD (TEQcal) of dust samples ranged from 134 to 531pg/g. In addition, the TEQcal of samples were significantly correlated with TEQbio of samples (R=0.83, P<0.01). The average daily doses (ADDs) of dioxins via indoor dust with the estimated ADDs of dioxins via air and food were compared. The results showed that indoor dust is an important medium of exposure to dioxins.
KW - EROD assay
KW - H4IIE
KW - TEQ
UR - http://www.scopus.com/inward/record.url?scp=79955490770&partnerID=8YFLogxK
U2 - 10.1016/j.ecoenv.2011.01.006
DO - 10.1016/j.ecoenv.2011.01.006
M3 - Journal article
C2 - 21300406
AN - SCOPUS:79955490770
SN - 0147-6513
VL - 74
SP - 947
EP - 952
JO - Ecotoxicology and Environmental Safety
JF - Ecotoxicology and Environmental Safety
IS - 4
ER -
