Chemical analysis of the Hedysarum multijugum root by HPLC fingerprinting

Yi Liu, Wei Wang, Yuying Zhao, Hubiao CHEN, Hong Liang, Qingying Zhang*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

4 Citations (Scopus)


The root of Hedysarum multijugum (RHM) is recorded as a folk herbal medicine in China and is sometimes used as a substitute for Hedysari Radix, which is a famous traditional Chinese medicine derived from the roots of Hedysarum polybotrys. In the present study, a sensible, reliable, and reproducible HPLCDAD fingerprint analysis method for RHM was developed and then subsequently applied to analyze RHM samples from different origins. The chemical constituents of the RHM samples were generally consistent, although it was slightly affected by the local environment of the plant. In addition, the chemical constituency of RHM was shown to be significantly different from that of Hedysari Radix, suggesting that RHM is not suitable as a substitute for Hedysari Radix, at least from the chemical point of view.

Original languageEnglish
Pages (from-to)654-659
Number of pages6
JournalJournal of Chinese Pharmaceutical Sciences
Issue number10
Publication statusPublished - 21 Oct 2015

Scopus Subject Areas

  • Pharmaceutical Science

User-Defined Keywords

  • Hedysarum
  • Hedysarum multijugum
  • HPLC fingerprint
  • Quality analysis
  • Species identification


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