TY - JOUR
T1 - Checking for normality in linear mixed models
AU - Wu, Ping
AU - ZHU, Lixing
AU - Fang, Yun
N1 - Funding Information:
Acknowledgements The research is supported in part by a grant of Research Grants Council of Hong Kong, and National Natural Science Foundation of China (Grant No. 11101157). The authors thank Christian Ritz for assistance with data.
PY - 2012/4
Y1 - 2012/4
N2 - Linear mixed models are popularly used to fit continuous longitudinal data, and the random effects are commonly assumed to have normal distribution. However, this assumption needs to be tested so that further analysis can be proceeded well. In this paper, we consider the Baringhaus-Henze-Epps-Pulley (BHEP) tests, which are based on an empirical characteristic function. Differing from their case, we consider the normality checking for the random effects which are unobservable and the test should be based on their predictors. The test is consistent against global alternatives, and is sensitive to the local alternatives converging to the null at a certain rate arbitrarily close to 1/√n where n is sample size. Furthermore, to overcome the problem that the limiting null distribution of the test is not tractable, we suggest a new method: use a conditional Monte Carlo test (CMCT) to approximate the null distribution, and then to simulate p-values. The test is compared with existing methods, the power is examined, and several examples are applied to illustrate the usefulness of our test in the analysis of longitudinal data.
AB - Linear mixed models are popularly used to fit continuous longitudinal data, and the random effects are commonly assumed to have normal distribution. However, this assumption needs to be tested so that further analysis can be proceeded well. In this paper, we consider the Baringhaus-Henze-Epps-Pulley (BHEP) tests, which are based on an empirical characteristic function. Differing from their case, we consider the normality checking for the random effects which are unobservable and the test should be based on their predictors. The test is consistent against global alternatives, and is sensitive to the local alternatives converging to the null at a certain rate arbitrarily close to 1/√n where n is sample size. Furthermore, to overcome the problem that the limiting null distribution of the test is not tractable, we suggest a new method: use a conditional Monte Carlo test (CMCT) to approximate the null distribution, and then to simulate p-values. The test is compared with existing methods, the power is examined, and several examples are applied to illustrate the usefulness of our test in the analysis of longitudinal data.
KW - BHEP tests
KW - conditional Monte Carlo test
KW - estimated best linear unbiased predictors
KW - linear mixed models
UR - http://www.scopus.com/inward/record.url?scp=84859269083&partnerID=8YFLogxK
U2 - 10.1007/s11425-011-4352-0
DO - 10.1007/s11425-011-4352-0
M3 - Journal article
AN - SCOPUS:84859269083
SN - 1674-7283
VL - 55
SP - 787
EP - 804
JO - Science China Mathematics
JF - Science China Mathematics
IS - 4
ER -