Characterization of Chemical Component Variations in Different Growth Years and Tissues of Morindae Officinalis Radix by Integrating Metabolomics and Glycomics

Ka Man Yip, Jun XU, Shan Shan Zhou, Yuk Man Lau, Qi Lei Chen, Yan Cheng Tang, Zhijun YANG, Zhong Ping Yao, Ping Ding*, Hubiao CHEN, Zhongzhen ZHAO

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Morindae Officinalis Radix (MOR), the dried root of Morinda officinalis F.C. How (Rubiaceae), is a popular food supplement in southeastern China for bone protection, andrological, and gynecological healthcare. In clinical use, 3-4 year old MOR is commonly used and the xylem is sometimes removed. However, there is no scientific rationale for these practices so far. In this study, metabolomics and glycomics were integrated using multiple chromatographic and mass spectrometric techniques coupled with multivariate statistical analysis to investigate the qualitative and quantitative variations of secondary metabolome and glycome in different growth years (1-7 years) and tissues (xylem and cortex) of MOR. The results showed that various types of bioactive components reached a maximum between 3 and 4 years of growth and that the xylem contained more potentially toxic constituents but less bioactive components than the cortex. This study provides the chemical basis for the common practice of using 3-4 year old MOR with the xylem removed.

Original languageEnglish
Pages (from-to)7304-7314
Number of pages11
JournalJournal of Agricultural and Food Chemistry
Volume67
Issue number26
DOIs
Publication statusPublished - 3 Jul 2019

Scopus Subject Areas

  • Chemistry(all)
  • Agricultural and Biological Sciences(all)

User-Defined Keywords

  • glycomics
  • growth year
  • metabolomics
  • Morindae Officianlis Radix
  • plant tissue
  • traditional practice

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