CaSH organocatalysis: Enantioselective Friedel-Crafts alkylation of indoles with α,β-unsaturated aldehydes

Tian Tian; Bao Jian Pei; Qing Hua Li; Hao He; Ling Yan Chen; Xiang Zhou; Wing Hong Chan; Albert W.M. Lee

doi:10.1055/s-0029-1217552

CaSH organocatalysis: Enantioselective Friedel-Crafts alkylation of indoles with α,β-unsaturated aldehydes

Tian Tian
, Bao Jian Pei
, Qing Hua Li
, Hao He
, Ling Yan Chen
, Xiang Zhou
, Wing Hong Chan
, Albert W.M. Lee

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

23 Citations (Scopus)

Abstract

Enantioselective Friedel-Crafts alkylation of indole with α,β-unsaturated aldehyde was catalyzed by camphor sulfonyl hydrazine (CaSH) with good enantioselectivity (81-88%).

Original language	English
Pages (from-to)	2115-2118
Number of pages	4
Journal	Synlett
Issue number	13
DOIs	https://doi.org/10.1055/s-0029-1217552
Publication status	Published - Aug 2009

User-Defined Keywords

α,β-unsaturated aldehydes
Camphor sulfonyl hydrazine (CaSH)
Indole alkylation
Organocatalysis

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10.1055/s-0029-1217552

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title = "CaSH organocatalysis: Enantioselective Friedel-Crafts alkylation of indoles with α,β-unsaturated aldehydes",

abstract = "Enantioselective Friedel-Crafts alkylation of indole with α,β-unsaturated aldehyde was catalyzed by camphor sulfonyl hydrazine (CaSH) with good enantioselectivity (81-88\%).",

keywords = "α,β-unsaturated aldehydes, Camphor sulfonyl hydrazine (CaSH), Indole alkylation, Organocatalysis",

author = "Tian Tian and Pei, \{Bao Jian\} and Li, \{Qing Hua\} and Hao He and Chen, \{Ling Yan\} and Xiang Zhou and Chan, \{Wing Hong\} and Lee, \{Albert W.M.\}",

year = "2009",

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T2 - Enantioselective Friedel-Crafts alkylation of indoles with α,β-unsaturated aldehydes

AU - Tian, Tian

AU - Pei, Bao Jian

AU - Li, Qing Hua

AU - He, Hao

AU - Chen, Ling Yan

AU - Zhou, Xiang

AU - Chan, Wing Hong

AU - Lee, Albert W.M.

PY - 2009/8

Y1 - 2009/8

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AB - Enantioselective Friedel-Crafts alkylation of indole with α,β-unsaturated aldehyde was catalyzed by camphor sulfonyl hydrazine (CaSH) with good enantioselectivity (81-88%).

KW - α,β-unsaturated aldehydes

KW - Camphor sulfonyl hydrazine (CaSH)

KW - Indole alkylation

KW - Organocatalysis

UR - https://www.scopus.com/pages/publications/68949141817

U2 - 10.1055/s-0029-1217552

DO - 10.1055/s-0029-1217552

M3 - Journal article

AN - SCOPUS:68949141817

SN - 0936-5214

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JO - Synlett

JF - Synlett

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ER -

CaSH organocatalysis: Enantioselective Friedel-Crafts alkylation of indoles with α,β-unsaturated aldehydes

Abstract

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