CaSH organocatalysis: Enantioselective Friedel-Crafts alkylation of indoles with α,β-unsaturated aldehydes

Tian Tian; Bao Jian Pei; Qing Hua Li; Hao He; Ling Yan Chen; Xiang Zhou; Wing Hong CHAN; Albert W M LEE

doi:10.1055/s-0029-1217552

CaSH organocatalysis: Enantioselective Friedel-Crafts alkylation of indoles with α,β-unsaturated aldehydes

Tian Tian, Bao Jian Pei, Qing Hua Li, Hao He, Ling Yan Chen, Xiang Zhou, Wing Hong CHAN, Albert W M LEE

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

22 Citations (Scopus)

Abstract

Enantioselective Friedel-Crafts alkylation of indole with α,β-unsaturated aldehyde was catalyzed by camphor sulfonyl hydrazine (CaSH) with good enantioselectivity (81-88%).

Original language	English
Pages (from-to)	2115-2118
Number of pages	4
Journal	Synlett
Issue number	13
DOIs	https://doi.org/10.1055/s-0029-1217552
Publication status	Published - Aug 2009

Scopus Subject Areas

Organic Chemistry

User-Defined Keywords

α,β-unsaturated aldehydes
Camphor sulfonyl hydrazine (CaSH)
Indole alkylation
Organocatalysis

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10.1055/s-0029-1217552

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title = "CaSH organocatalysis: Enantioselective Friedel-Crafts alkylation of indoles with α,β-unsaturated aldehydes",

abstract = "Enantioselective Friedel-Crafts alkylation of indole with α,β-unsaturated aldehyde was catalyzed by camphor sulfonyl hydrazine (CaSH) with good enantioselectivity (81-88%).",

keywords = "α,β-unsaturated aldehydes, Camphor sulfonyl hydrazine (CaSH), Indole alkylation, Organocatalysis",

author = "Tian Tian and Pei, {Bao Jian} and Li, {Qing Hua} and Hao He and Chen, {Ling Yan} and Xiang Zhou and CHAN, {Wing Hong} and LEE, {Albert W M}",

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T2 - Enantioselective Friedel-Crafts alkylation of indoles with α,β-unsaturated aldehydes

AU - Tian, Tian

AU - Pei, Bao Jian

AU - Li, Qing Hua

AU - He, Hao

AU - Chen, Ling Yan

AU - Zhou, Xiang

AU - CHAN, Wing Hong

AU - LEE, Albert W M

PY - 2009/8

Y1 - 2009/8

N2 - Enantioselective Friedel-Crafts alkylation of indole with α,β-unsaturated aldehyde was catalyzed by camphor sulfonyl hydrazine (CaSH) with good enantioselectivity (81-88%).

AB - Enantioselective Friedel-Crafts alkylation of indole with α,β-unsaturated aldehyde was catalyzed by camphor sulfonyl hydrazine (CaSH) with good enantioselectivity (81-88%).

KW - α,β-unsaturated aldehydes

KW - Camphor sulfonyl hydrazine (CaSH)

KW - Indole alkylation

KW - Organocatalysis

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DO - 10.1055/s-0029-1217552

M3 - Journal article

AN - SCOPUS:68949141817

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JO - Synlett

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ER -

CaSH organocatalysis: Enantioselective Friedel-Crafts alkylation of indoles with α,β-unsaturated aldehydes

Abstract

Scopus Subject Areas

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