CaSH organocatalysis: Enantioselective Friedel-Crafts alkylation of indoles with α,β-unsaturated aldehydes

Tian Tian, Bao Jian Pei, Qing Hua Li, Hao He, Ling Yan Chen, Xiang Zhou, Wing Hong CHAN, Albert W M LEE

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Enantioselective Friedel-Crafts alkylation of indole with α,β-unsaturated aldehyde was catalyzed by camphor sulfonyl hydrazine (CaSH) with good enantioselectivity (81-88%).

Original languageEnglish
Pages (from-to)2115-2118
Number of pages4
JournalSynlett
Issue number13
DOIs
Publication statusPublished - Aug 2009

Scopus Subject Areas

  • Organic Chemistry

User-Defined Keywords

  • α,β-unsaturated aldehydes
  • Camphor sulfonyl hydrazine (CaSH)
  • Indole alkylation
  • Organocatalysis

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