Carbazole-based two-photon fluorescent probe for selective imaging of mitochondrial hydrogen peroxide in living cells and tissues

Kai Zhang, Wei Wu, Yinhui Li*, Mingtai Sun, Huan Yu, Ricky M S WONG

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

17 Citations (Scopus)

Abstract

This paper reported a two-photon fluorescent probe for mitochondrial H2O2 detection and imaging based on the incorporation of a sensing boronate ester and an organelle-targeting triphenylphosphonium moiety onto the carbazole fluorophore. The probe exhibits a fast “turn on” response, good selectivity toward H2O2 and high specificity for mitochondria.

Original languageEnglish
Pages (from-to)115298-115302
Number of pages5
JournalRSC Advances
Volume6
Issue number116
DOIs
Publication statusPublished - 2016

Scopus Subject Areas

  • General Chemistry
  • General Chemical Engineering

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