Cancer risk assessment of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) in former agricultural soils of Hong Kong

Yu Bon Man; Brenda Natalia Lopez; Hong Sheng Wang; Anna Oi Wah Leung; Ka Lai Chow; Ming H. Wong

doi:10.1016/j.jhazmat.2011.08.010

Cancer risk assessment of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) in former agricultural soils of Hong Kong

Yu Bon Man, Brenda Natalia Lopez, Hong Sheng Wang, Anna Oi Wah Leung, Ka Lai Chow, Ming H. Wong^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › peer-review

62 Citations (Scopus)

Abstract

The major objective of this study was to evaluate the carcinogenic risk posed to humans through PBDEs and PCBs of changing agricultural land use for recycling of e-waste and open burning of municipal waste. Nine locations were selected to represent 6 different types of land use such as e-waste dismantling workshop (EW (DW)) and e-waste open burning site (EW (OBS)). The total concentrations for PBDEs and PCBs, and the bioaccessibility of PCBs were determined using Soxhlet extraction and in vitro simulated gastric solution, respectively. Both total and bioaccessible concentrations were subsequently used to establish the cancer risk probabilities in humans via ingestion, dermal contact and inhalation of soil particles. It was found that very low cancer risk in all 6 types of different land use was caused by BDE-209. Nevertheless, at the 95th centile, the concentration of PCBs in EW (DW) and EW (OBS) indicate a low cancer risk to humans of 40 and 2.1 in a million, respectively, while the same was also observed for the bioaccessible PCBs in EW (DW) of 1.71 ± 2.96 in a million.

Original language	English
Pages (from-to)	92-99
Number of pages	8
Journal	Journal of Hazardous Materials
Volume	195
DOIs	https://doi.org/10.1016/j.jhazmat.2011.08.010
Publication status	Published - 15 Nov 2011

Scopus Subject Areas

Environmental Engineering
Environmental Chemistry
Waste Management and Disposal
Pollution
Health, Toxicology and Mutagenesis

User-Defined Keywords

Farm soils
Land use change
Lifetime cancer risk
PBDEs
PCBs

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.jhazmat.2011.08.010

Cite this

@article{9adc7e7c2f2a4d9994b8102d0c336392,

title = "Cancer risk assessment of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) in former agricultural soils of Hong Kong",

abstract = "The major objective of this study was to evaluate the carcinogenic risk posed to humans through PBDEs and PCBs of changing agricultural land use for recycling of e-waste and open burning of municipal waste. Nine locations were selected to represent 6 different types of land use such as e-waste dismantling workshop (EW (DW)) and e-waste open burning site (EW (OBS)). The total concentrations for PBDEs and PCBs, and the bioaccessibility of PCBs were determined using Soxhlet extraction and in vitro simulated gastric solution, respectively. Both total and bioaccessible concentrations were subsequently used to establish the cancer risk probabilities in humans via ingestion, dermal contact and inhalation of soil particles. It was found that very low cancer risk in all 6 types of different land use was caused by BDE-209. Nevertheless, at the 95th centile, the concentration of PCBs in EW (DW) and EW (OBS) indicate a low cancer risk to humans of 40 and 2.1 in a million, respectively, while the same was also observed for the bioaccessible PCBs in EW (DW) of 1.71 ± 2.96 in a million.",

keywords = "Farm soils, Land use change, Lifetime cancer risk, PBDEs, PCBs",

author = "Man, {Yu Bon} and Lopez, {Brenda Natalia} and Wang, {Hong Sheng} and Leung, {Anna Oi Wah} and Chow, {Ka Lai} and Wong, {Ming H.}",

note = "Funding Information: The authors would like to thank the Public Policy Research Grants ( 2002-PPR-3 ), Special Equipment Grant ( SEG HKBUO09 ) of the Research Grants Council of Hong Kong and the Mini-AoE (Areas of Excellence) Fund from Hong Kong Baptist University ( RC/AoE/08–09/01 ) for financial support. ",

year = "2011",

month = nov,

day = "15",

doi = "10.1016/j.jhazmat.2011.08.010",

language = "English",

volume = "195",

pages = "92--99",

journal = "Journal of Hazardous Materials",

issn = "0304-3894",

publisher = "Elsevier",

}

TY - JOUR

T1 - Cancer risk assessment of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) in former agricultural soils of Hong Kong

AU - Man, Yu Bon

AU - Lopez, Brenda Natalia

AU - Wang, Hong Sheng

AU - Leung, Anna Oi Wah

AU - Chow, Ka Lai

AU - Wong, Ming H.

N1 - Funding Information: The authors would like to thank the Public Policy Research Grants ( 2002-PPR-3 ), Special Equipment Grant ( SEG HKBUO09 ) of the Research Grants Council of Hong Kong and the Mini-AoE (Areas of Excellence) Fund from Hong Kong Baptist University ( RC/AoE/08–09/01 ) for financial support.

PY - 2011/11/15

Y1 - 2011/11/15

N2 - The major objective of this study was to evaluate the carcinogenic risk posed to humans through PBDEs and PCBs of changing agricultural land use for recycling of e-waste and open burning of municipal waste. Nine locations were selected to represent 6 different types of land use such as e-waste dismantling workshop (EW (DW)) and e-waste open burning site (EW (OBS)). The total concentrations for PBDEs and PCBs, and the bioaccessibility of PCBs were determined using Soxhlet extraction and in vitro simulated gastric solution, respectively. Both total and bioaccessible concentrations were subsequently used to establish the cancer risk probabilities in humans via ingestion, dermal contact and inhalation of soil particles. It was found that very low cancer risk in all 6 types of different land use was caused by BDE-209. Nevertheless, at the 95th centile, the concentration of PCBs in EW (DW) and EW (OBS) indicate a low cancer risk to humans of 40 and 2.1 in a million, respectively, while the same was also observed for the bioaccessible PCBs in EW (DW) of 1.71 ± 2.96 in a million.

AB - The major objective of this study was to evaluate the carcinogenic risk posed to humans through PBDEs and PCBs of changing agricultural land use for recycling of e-waste and open burning of municipal waste. Nine locations were selected to represent 6 different types of land use such as e-waste dismantling workshop (EW (DW)) and e-waste open burning site (EW (OBS)). The total concentrations for PBDEs and PCBs, and the bioaccessibility of PCBs were determined using Soxhlet extraction and in vitro simulated gastric solution, respectively. Both total and bioaccessible concentrations were subsequently used to establish the cancer risk probabilities in humans via ingestion, dermal contact and inhalation of soil particles. It was found that very low cancer risk in all 6 types of different land use was caused by BDE-209. Nevertheless, at the 95th centile, the concentration of PCBs in EW (DW) and EW (OBS) indicate a low cancer risk to humans of 40 and 2.1 in a million, respectively, while the same was also observed for the bioaccessible PCBs in EW (DW) of 1.71 ± 2.96 in a million.

KW - Farm soils

KW - Land use change

KW - Lifetime cancer risk

KW - PBDEs

KW - PCBs

UR - http://www.scopus.com/inward/record.url?scp=80054098148&partnerID=8YFLogxK

U2 - 10.1016/j.jhazmat.2011.08.010

DO - 10.1016/j.jhazmat.2011.08.010

M3 - Journal article

C2 - 21871716

AN - SCOPUS:80054098148

SN - 0304-3894

VL - 195

SP - 92

EP - 99

JO - Journal of Hazardous Materials

JF - Journal of Hazardous Materials

ER -

Cancer risk assessment of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) in former agricultural soils of Hong Kong

Abstract

Scopus Subject Areas

User-Defined Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this