TY - JOUR
T1 - Brassinosteroid-Activated BRI1-EMS-SUPPRESSOR 1 Inhibits Flavonoid Biosynthesis and Coordinates Growth and UV-B Stress Responses in Plants
AU - Liang, Tong
AU - Shi, Chen
AU - Peng, Yao
AU - Tan, Huijuan
AU - Xin, Peiyong
AU - Yang, Yu
AU - Wang, Fei
AU - Li, Xu
AU - Chu, Jinfang
AU - Huang, Jirong
AU - Yin, Yanhai
AU - Liu, Hongtao
N1 - This work was supported by grants from the National Key Research and Development Program of China (grant 2016YFD0100404), the National Natural Science Foundation of China (grants 31825004, 31721001, 31730009, 31670282, 31670307, and 31470433), the Strategic Priority Research Program of the Chinese Academy of Sciences (grant XDB27030000), the Program of Shanghai Academic Research Leader, and the National Institute of General Medical Sciences (to Y.Y.).
Publisher Copyright:
© 2020 American Society of Plant Biologists. All rights reserved.
PY - 2020/10
Y1 - 2020/10
N2 - UV-B light is a potential stress factor in plants, but how plants coordinate growth and UV-B stress responses is not well understood. Here, we report that brassinosteroid (BR) signaling inhibits UV-B stress responses in Arabidopsis (Arabidopsis thaliana) and various crops by controlling flavonol biosynthesis. We further demonstrate that BRI1-EMS-SUPPRESSOR 1 (BES1) mediates the tradeoff between plant growth and UV-B defense responses. BES1, a master transcription factor involved in BR signaling, represses the expression of transcription factor genes MYB11, MYB12, and MYB111, which activate flavonol biosynthesis. BES1 directly binds to the promoters of these MYBs in a BR-enhanced manner to repress their expression, thereby reducing flavonol accumulation. However, exposure to broadband UV-B down-regulates BES1 expression, thus promoting flavonol accumulation. These findings demonstrate that BR-activated BES1 not only promotes growth but also inhibits flavonoid biosynthesis. UV-B stress suppresses the expression of BES1 to allocate energy to flavonoid biosynthesis and UV-B stress responses, allowing plants to switch from growth to UV-B stress responses in a timely manner.
AB - UV-B light is a potential stress factor in plants, but how plants coordinate growth and UV-B stress responses is not well understood. Here, we report that brassinosteroid (BR) signaling inhibits UV-B stress responses in Arabidopsis (Arabidopsis thaliana) and various crops by controlling flavonol biosynthesis. We further demonstrate that BRI1-EMS-SUPPRESSOR 1 (BES1) mediates the tradeoff between plant growth and UV-B defense responses. BES1, a master transcription factor involved in BR signaling, represses the expression of transcription factor genes MYB11, MYB12, and MYB111, which activate flavonol biosynthesis. BES1 directly binds to the promoters of these MYBs in a BR-enhanced manner to repress their expression, thereby reducing flavonol accumulation. However, exposure to broadband UV-B down-regulates BES1 expression, thus promoting flavonol accumulation. These findings demonstrate that BR-activated BES1 not only promotes growth but also inhibits flavonoid biosynthesis. UV-B stress suppresses the expression of BES1 to allocate energy to flavonoid biosynthesis and UV-B stress responses, allowing plants to switch from growth to UV-B stress responses in a timely manner.
UR - https://www.scopus.com/pages/publications/85092682006
U2 - 10.1105/tpc.20.00048
DO - 10.1105/tpc.20.00048
M3 - Journal article
C2 - 32796123
AN - SCOPUS:85092682006
SN - 1040-4651
VL - 32
SP - 3224
EP - 3239
JO - Plant Cell
JF - Plant Cell
IS - 10
ER -
