Both visual and ratiometric fluorescent sensor for Zn 2+ based on spirobenzopyran platform

Jian Fa Zhu; Wing Hong Chan; Albert W.M. Lee

doi:10.1016/j.tetlet.2012.02.031

Both visual and ratiometric fluorescent sensor for Zn ²⁺ based on spirobenzopyran platform

Jian Fa Zhu, Wing Hong Chan^*, Albert W.M. Lee

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

36 Citations (Scopus)

Abstract

A ratiometric fluorescent Zn ²⁺ chemosensor, SPQH, based on spirobenzopyran platform, was synthesized. In aqueous HEPES 7.4 buffer solution, upon chelation with Zn(II), SPQH demonstrates high selectivity and subnanomolar sensitivity for zinc ion with 36-fold enhancement in the NIR fluorescence output.

Original language	English
Pages (from-to)	2001-2004
Number of pages	4
Journal	Tetrahedron Letters
Volume	53
Issue number	15
DOIs	https://doi.org/10.1016/j.tetlet.2012.02.031
Publication status	Published - 11 Apr 2012

Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

User-Defined Keywords

Fluorescent
Ratiometric
Spirobenzopyran
Zn chemosensor

Access to Document

10.1016/j.tetlet.2012.02.031

Cite this

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title = "Both visual and ratiometric fluorescent sensor for Zn 2+ based on spirobenzopyran platform",

abstract = "A ratiometric fluorescent Zn 2+ chemosensor, SPQH, based on spirobenzopyran platform, was synthesized. In aqueous HEPES 7.4 buffer solution, upon chelation with Zn(II), SPQH demonstrates high selectivity and subnanomolar sensitivity for zinc ion with 36-fold enhancement in the NIR fluorescence output.",

keywords = "Fluorescent, Ratiometric, Spirobenzopyran, Zn chemosensor",

author = "Zhu, {Jian Fa} and Chan, {Wing Hong} and Lee, {Albert W.M.}",

note = "Funding Information: The financial supports from the Research Grant Council of Hong Kong ( HKBU 200407 ) and Hong Kong Baptist University ( FRGI/10-11/026 ) are acknowledged. ",

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T1 - Both visual and ratiometric fluorescent sensor for Zn 2+ based on spirobenzopyran platform

AU - Zhu, Jian Fa

AU - Chan, Wing Hong

AU - Lee, Albert W.M.

N1 - Funding Information: The financial supports from the Research Grant Council of Hong Kong ( HKBU 200407 ) and Hong Kong Baptist University ( FRGI/10-11/026 ) are acknowledged.

PY - 2012/4/11

Y1 - 2012/4/11

N2 - A ratiometric fluorescent Zn 2+ chemosensor, SPQH, based on spirobenzopyran platform, was synthesized. In aqueous HEPES 7.4 buffer solution, upon chelation with Zn(II), SPQH demonstrates high selectivity and subnanomolar sensitivity for zinc ion with 36-fold enhancement in the NIR fluorescence output.

AB - A ratiometric fluorescent Zn 2+ chemosensor, SPQH, based on spirobenzopyran platform, was synthesized. In aqueous HEPES 7.4 buffer solution, upon chelation with Zn(II), SPQH demonstrates high selectivity and subnanomolar sensitivity for zinc ion with 36-fold enhancement in the NIR fluorescence output.

KW - Fluorescent

KW - Ratiometric

KW - Spirobenzopyran

KW - Zn chemosensor

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