Both visual and ratiometric fluorescent sensor for Zn 2+ based on spirobenzopyran platform

Jian Fa Zhu, Wing Hong CHAN*, Albert W M LEE

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)


A ratiometric fluorescent Zn 2+ chemosensor, SPQH, based on spirobenzopyran platform, was synthesized. In aqueous HEPES 7.4 buffer solution, upon chelation with Zn(II), SPQH demonstrates high selectivity and subnanomolar sensitivity for zinc ion with 36-fold enhancement in the NIR fluorescence output.

Original languageEnglish
Pages (from-to)2001-2004
Number of pages4
JournalTetrahedron Letters
Issue number15
Publication statusPublished - 11 Apr 2012

Scopus Subject Areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

User-Defined Keywords

  • Fluorescent
  • Ratiometric
  • Spirobenzopyran
  • Zn chemosensor


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