Biological Applications of Supramolecular Coordination Complexes

Chung Hang Leung*, Tian Shu Kang, Chao Yang, Ka Ho Leung, Edmond Dik Lung MA

*Corresponding author for this work

Research output: Chapter in book/report/conference proceedingChapterpeer-review

3 Citations (Scopus)

Abstract

Mononuclear metal complexes, particularly those based on platinum and ruthenium metal centers, have attracted tremendous attention over recent decades for therapeutic purposes, particular anticancer therapy. However, inorganic architectures based on supramolecular coordination complexes (SCCs) have received comparatively less attention for biological applications. In this chapter, we highlight recent examples of SCCs that interact with DNA or protein through different binding modes and/or exhibit cytotoxic activity against cancer cell lines.

Original languageEnglish
Title of host publicationSupramolecular Medicinal Chemistry and Chemical Biology
PublisherElsevier Inc.
Pages3-20
Number of pages18
Volume5
ISBN (Electronic)9780128031988
ISBN (Print)9780128031995
DOIs
Publication statusPublished - 22 Jun 2017

Scopus Subject Areas

  • Chemistry(all)

User-Defined Keywords

  • Anticancer
  • Biological
  • Coordination
  • Drug
  • Inorganic
  • Medicinal chemistry
  • Metal complex
  • Supramolecular
  • Therapeutic
  • Transition metal

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