Bioelectric signaling as an emerging layer of macrophage communication

Weijia Zheng; Yitao Li; Wei Jia

doi:10.1016/j.it.2026.05.005

Bioelectric signaling as an emerging layer of macrophage communication

Weijia Zheng (Co-first author)
, Yitao Li (Co-first author)
, Wei Jia^*

^*Corresponding author for this work

Chinese Medicine - Teaching and Research Division

Research output: Contribution to journal › Journal article › peer-review

Abstract

Bioelectric signaling may represent an emerging layer of macrophage communication. This forum discusses how membrane-potential dynamics, ion fluxes, and context-dependent intercellular coupling may coordinate macrophage responses within tissues, highlighting a potential new dimension of immune regulation with broad implications for tissue-level immunity.

Original language	English
Journal	Trends in Immunology
DOIs	https://doi.org/10.1016/j.it.2026.05.005
Publication status	E-pub ahead of print - 10 Jun 2026

User-Defined Keywords

bioelectric signaling
ion channels
macrophage polarization
metabolic syndrome
tissue-resident macrophages

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10.1016/j.it.2026.05.005

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@article{148f1cc668bf40e48fec621859e1a1a3,

title = "Bioelectric signaling as an emerging layer of macrophage communication",

abstract = "Bioelectric signaling may represent an emerging layer of macrophage communication. This forum discusses how membrane-potential dynamics, ion fluxes, and context-dependent intercellular coupling may coordinate macrophage responses within tissues, highlighting a potential new dimension of immune regulation with broad implications for tissue-level immunity.",

keywords = "bioelectric signaling, ion channels, macrophage polarization, metabolic syndrome, tissue-resident macrophages",

author = "Weijia Zheng and Yitao Li and Wei Jia",

note = "Publisher Copyright: {\textcopyright} 2026 Department of Pharmacology and Pharmacy, the University of Hong Kong, Hong Kong",

year = "2026",

month = jun,

day = "10",

doi = "10.1016/j.it.2026.05.005",

language = "English",

journal = "Trends in Immunology",

issn = "1471-4906",

publisher = "Elsevier Ltd.",

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TY - JOUR

T1 - Bioelectric signaling as an emerging layer of macrophage communication

AU - Zheng, Weijia

AU - Li, Yitao

AU - Jia, Wei

PY - 2026/6/10

Y1 - 2026/6/10

N2 - Bioelectric signaling may represent an emerging layer of macrophage communication. This forum discusses how membrane-potential dynamics, ion fluxes, and context-dependent intercellular coupling may coordinate macrophage responses within tissues, highlighting a potential new dimension of immune regulation with broad implications for tissue-level immunity.

AB - Bioelectric signaling may represent an emerging layer of macrophage communication. This forum discusses how membrane-potential dynamics, ion fluxes, and context-dependent intercellular coupling may coordinate macrophage responses within tissues, highlighting a potential new dimension of immune regulation with broad implications for tissue-level immunity.

KW - bioelectric signaling

KW - ion channels

KW - macrophage polarization

KW - metabolic syndrome

KW - tissue-resident macrophages

UR - https://www.scopus.com/pages/publications/105041465445

U2 - 10.1016/j.it.2026.05.005

DO - 10.1016/j.it.2026.05.005

M3 - Journal article

SN - 1471-4906

JO - Trends in Immunology

JF - Trends in Immunology

ER -

Bioelectric signaling as an emerging layer of macrophage communication

Abstract

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