Biocompatible CdSe quantum dot-based photosensitizer under two-photon excitation for photodynamic therapy

Zu De Qi, Dong Wei Li, Peng Jiang, Feng Lei Jiang, Yue Sheng Li, Yi Liu*, Rick W K WONG, Kok Wai CHEAH

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

74 Citations (Scopus)

Abstract

An enhanced photosensitizer combining biocompatible CdSe quantum dots (QDs) with water-soluble porphyrin was synthesized by a facile method. The two photon absorption (TPA) cross-section values of the QDs range from 800 to 2400 Goeppert-Mayer units (GM), depending on the excitation wavelength, calculated by the standard method using R6G as a reference. The singlet oxygen generation under two-photon excitation (TPE) in the QD-porphyrin system was two times greater than that in the porphyrin solution alone. This study underlines the potential of QD-based photosensitizers for biological applications in TPE photodynamic therapy.

Original languageEnglish
Pages (from-to)2455-2458
Number of pages4
JournalJournal of Materials Chemistry
Volume21
Issue number8
DOIs
Publication statusPublished - 28 Feb 2011

Scopus Subject Areas

  • Chemistry(all)
  • Materials Chemistry

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