Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential

Kam Lok Wong, Ricky Ngok Shun Wong, Liang Zhang, Wing Keung Liu, Tzi Bun Ng, Pang Chui Shaw, Philip Chi Lip Kwok, Yau Ming Lai, Zhang Jin Zhang, Yanbo Zhang, Yao Tong, Ho Pan Cheung, Jia Lu, Stephen Cho Wing Sze*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

41 Citations (Scopus)

Abstract

Some protein pharmaceuticals from Chinese medicine have been developed to treat cardiovascular diseases, genetic diseases, and cancer. Bioactive proteins with various pharmacological properties have been successfully isolated from animals such as Hirudo medicinalis (medicinal leech), Eisenia fetida (earthworm), and Mesobuthus martensii (Chinese scorpion), and from herbal medicines derived from species such as Cordyceps militaris, Ganoderma, Momordica cochinchinensis, Viscum album, Poria cocos, Senna obtusifolia, Panax notoginseng, Smilax glabra, Ginkgo biloba, Dioscorea batatas, and Trichosanthes kirilowii. This article reviews the isolation methods, molecular characteristics, bioactivities, pharmacological properties, and potential uses of bioactive proteins originating from these Chinese medicines.

Original languageEnglish
Article number19
Number of pages14
JournalChinese Medicine
Volume9
DOIs
Publication statusPublished - 19 Jul 2014

Scopus Subject Areas

  • Pharmacology
  • Complementary and alternative medicine

User-Defined Keywords

  • Chinese Medicine
  • Bivalirudin
  • Fibrinolytic Enzyme
  • Fast Protein Liquid Chromatography
  • Viscum Album

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