Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential

Kam L. Wong; Ricky N S WONG; Liang Zhang; Wing K. Liu; Tzi B. NG; Pang C. Shaw; Philip Chi L. Kwok; Yau M. Lai; Zhang J. Zhang; Yanbo Zhang; Yao Tong; Ho Pan Cheung; Jia Lu; Cho Wing SZE

doi:10.1186/1749-8546-9-19

Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential

Kam L. Wong, Ricky N S WONG, Liang Zhang, Wing K. Liu, Tzi B. NG, Pang C. Shaw, Philip Chi L. Kwok, Yau M. Lai, Zhang J. Zhang, Yanbo Zhang, Yao Tong, Ho Pan Cheung, Jia Lu, Cho Wing SZE^*

^*Corresponding author for this work

Department of Biology

Research output: Contribution to journal › Review article › peer-review

36 Citations (Scopus)

Abstract

Some protein pharmaceuticals from Chinese medicine have been developed to treat cardiovascular diseases, genetic diseases, and cancer. Bioactive proteins with various pharmacological properties have been successfully isolated from animals such as Hirudo medicinalis (medicinal leech), Eisenia fetida (earthworm), and Mesobuthus martensii (Chinese scorpion), and from herbal medicines derived from species such as Cordyceps militaris, Ganoderma, Momordica cochinchinensis, Viscum album, Poria cocos, Senna obtusifolia, Panax notoginseng, Smilax glabra, Ginkgo biloba, Dioscorea batatas, and Trichosanthes kirilowii. This article reviews the isolation methods, molecular characteristics, bioactivities, pharmacological properties, and potential uses of bioactive proteins originating from these Chinese medicines.

Original language	English
Article number	19
Journal	Chinese Medicine
Volume	9
Issue number	1
DOIs	https://doi.org/10.1186/1749-8546-9-19
Publication status	Published - 19 Jul 2014

Scopus Subject Areas

Pharmacology
Complementary and alternative medicine

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1186/1749-8546-9-19

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title = "Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential",

abstract = "Some protein pharmaceuticals from Chinese medicine have been developed to treat cardiovascular diseases, genetic diseases, and cancer. Bioactive proteins with various pharmacological properties have been successfully isolated from animals such as Hirudo medicinalis (medicinal leech), Eisenia fetida (earthworm), and Mesobuthus martensii (Chinese scorpion), and from herbal medicines derived from species such as Cordyceps militaris, Ganoderma, Momordica cochinchinensis, Viscum album, Poria cocos, Senna obtusifolia, Panax notoginseng, Smilax glabra, Ginkgo biloba, Dioscorea batatas, and Trichosanthes kirilowii. This article reviews the isolation methods, molecular characteristics, bioactivities, pharmacological properties, and potential uses of bioactive proteins originating from these Chinese medicines.",

author = "Wong, {Kam L.} and WONG, {Ricky N S} and Liang Zhang and Liu, {Wing K.} and NG, {Tzi B.} and Shaw, {Pang C.} and Kwok, {Philip Chi L.} and Lai, {Yau M.} and Zhang, {Zhang J.} and Yanbo Zhang and Yao Tong and Cheung, {Ho Pan} and Jia Lu and SZE, {Cho Wing}",

year = "2014",

month = jul,

day = "19",

doi = "10.1186/1749-8546-9-19",

language = "English",

volume = "9",

journal = "Chinese Medicine",

issn = "1749-8546",

publisher = "BioMed Central Ltd.",

number = "1",

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TY - JOUR

T1 - Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential

AU - Wong, Kam L.

AU - WONG, Ricky N S

AU - Zhang, Liang

AU - Liu, Wing K.

AU - NG, Tzi B.

AU - Shaw, Pang C.

AU - Kwok, Philip Chi L.

AU - Lai, Yau M.

AU - Zhang, Zhang J.

AU - Zhang, Yanbo

AU - Tong, Yao

AU - Cheung, Ho Pan

AU - Lu, Jia

AU - SZE, Cho Wing

PY - 2014/7/19

Y1 - 2014/7/19

N2 - Some protein pharmaceuticals from Chinese medicine have been developed to treat cardiovascular diseases, genetic diseases, and cancer. Bioactive proteins with various pharmacological properties have been successfully isolated from animals such as Hirudo medicinalis (medicinal leech), Eisenia fetida (earthworm), and Mesobuthus martensii (Chinese scorpion), and from herbal medicines derived from species such as Cordyceps militaris, Ganoderma, Momordica cochinchinensis, Viscum album, Poria cocos, Senna obtusifolia, Panax notoginseng, Smilax glabra, Ginkgo biloba, Dioscorea batatas, and Trichosanthes kirilowii. This article reviews the isolation methods, molecular characteristics, bioactivities, pharmacological properties, and potential uses of bioactive proteins originating from these Chinese medicines.

AB - Some protein pharmaceuticals from Chinese medicine have been developed to treat cardiovascular diseases, genetic diseases, and cancer. Bioactive proteins with various pharmacological properties have been successfully isolated from animals such as Hirudo medicinalis (medicinal leech), Eisenia fetida (earthworm), and Mesobuthus martensii (Chinese scorpion), and from herbal medicines derived from species such as Cordyceps militaris, Ganoderma, Momordica cochinchinensis, Viscum album, Poria cocos, Senna obtusifolia, Panax notoginseng, Smilax glabra, Ginkgo biloba, Dioscorea batatas, and Trichosanthes kirilowii. This article reviews the isolation methods, molecular characteristics, bioactivities, pharmacological properties, and potential uses of bioactive proteins originating from these Chinese medicines.

UR - http://www.scopus.com/inward/record.url?scp=84904520078&partnerID=8YFLogxK

U2 - 10.1186/1749-8546-9-19

DO - 10.1186/1749-8546-9-19

M3 - Review article

AN - SCOPUS:84904520078

SN - 1749-8546

VL - 9

JO - Chinese Medicine

JF - Chinese Medicine

IS - 1

M1 - 19

ER -

Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential

Abstract

Scopus Subject Areas

UN SDGs

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