Bioaccessibility of polychlorinated biphenyls in workplace dust and its implication for risk assessment

Yuan Kang; Yi Yin; Yubon Man; Laisheng Li; Qiuyun Zhang; Lixuan Zeng; Jiwen Luo; Ming Hung Wong

doi:10.1016/j.chemosphere.2013.05.057

Bioaccessibility of polychlorinated biphenyls in workplace dust and its implication for risk assessment

Yuan Kang^*, Yi Yin, Yubon Man, Laisheng Li, Qiuyun Zhang, Lixuan Zeng, Jiwen Luo, Ming Hung Wong

^*Corresponding author for this work

Department of Biology

Research output: Contribution to journal › Journal article › peer-review

30 Citations (Scopus)

Abstract

Human exposure to bioaccessible PCBs via indoor dust is limited around the world. In the present study, the workplace dust sample from commercial office, hospital, secondary school, shopping mall, electronic factory and manufacturing plant were collected from Hong Kong for PCBs analyses. Total PCBs concentrations ranged from 46.8 to 249ngg^-1, with a median of 107ngg^-1. Manufacturing plant showed the highest concentration among all of sampling sites. PCB 77 was found as the dominant congeners. The bioaccessibility of PCBs in small intestinal juice ranging from 8.3% to 26.0% was significantly higher than that in gastric condition, ranging from 4.8% to 12.4%. In addition, significant negative correlations (p<0.05) were observed between K_OW and bioaccessibility for all workplace dust samples. Risk assessment indicated that the averaged daily dose of dioxin-like PCBs via non-dietary intake of workplace dust, considering the bioaccessibility of PCBs, were much lower than the TDI of dioxins (2.3pg WHO-TEQ kgbw^-1d^-1) established by Joint FAO/WHO Expert Committee on Food Additives.

Original language	English
Pages (from-to)	924-930
Number of pages	7
Journal	Chemosphere
Volume	93
Issue number	6
DOIs	https://doi.org/10.1016/j.chemosphere.2013.05.057
Publication status	Published - Oct 2013

Scopus Subject Areas

Environmental Engineering
Environmental Chemistry
General Chemistry
Pollution
Health, Toxicology and Mutagenesis

User-Defined Keywords

Bioaccessibility
PCBs
Risk Assessment
Workplace dust

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10.1016/j.chemosphere.2013.05.057

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@article{39d5d4396b1e4bbeaeafc1ed0de1659e,

title = "Bioaccessibility of polychlorinated biphenyls in workplace dust and its implication for risk assessment",

abstract = "Human exposure to bioaccessible PCBs via indoor dust is limited around the world. In the present study, the workplace dust sample from commercial office, hospital, secondary school, shopping mall, electronic factory and manufacturing plant were collected from Hong Kong for PCBs analyses. Total PCBs concentrations ranged from 46.8 to 249ngg-1, with a median of 107ngg-1. Manufacturing plant showed the highest concentration among all of sampling sites. PCB 77 was found as the dominant congeners. The bioaccessibility of PCBs in small intestinal juice ranging from 8.3% to 26.0% was significantly higher than that in gastric condition, ranging from 4.8% to 12.4%. In addition, significant negative correlations (p<0.05) were observed between KOW and bioaccessibility for all workplace dust samples. Risk assessment indicated that the averaged daily dose of dioxin-like PCBs via non-dietary intake of workplace dust, considering the bioaccessibility of PCBs, were much lower than the TDI of dioxins (2.3pg WHO-TEQ kgbw-1d-1) established by Joint FAO/WHO Expert Committee on Food Additives.",

keywords = "Bioaccessibility, PCBs, Risk Assessment, Workplace dust",

author = "Yuan Kang and Yi Yin and Yubon Man and Laisheng Li and Qiuyun Zhang and Lixuan Zeng and Jiwen Luo and Wong, {Ming Hung}",

note = "Funding Information: Young Scientist Incubation Fund of South China Normal University and Mini-AoE (Area of Excellence, RC/AOE/08-09/01 ) Fund from Hong Kong Baptist University are gratefully acknowledged.",

year = "2013",

month = oct,

doi = "10.1016/j.chemosphere.2013.05.057",

language = "English",

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pages = "924--930",

journal = "Chemosphere",

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T1 - Bioaccessibility of polychlorinated biphenyls in workplace dust and its implication for risk assessment

AU - Kang, Yuan

AU - Yin, Yi

AU - Man, Yubon

AU - Li, Laisheng

AU - Zhang, Qiuyun

AU - Zeng, Lixuan

AU - Luo, Jiwen

AU - Wong, Ming Hung

N1 - Funding Information: Young Scientist Incubation Fund of South China Normal University and Mini-AoE (Area of Excellence, RC/AOE/08-09/01 ) Fund from Hong Kong Baptist University are gratefully acknowledged.

PY - 2013/10

Y1 - 2013/10

N2 - Human exposure to bioaccessible PCBs via indoor dust is limited around the world. In the present study, the workplace dust sample from commercial office, hospital, secondary school, shopping mall, electronic factory and manufacturing plant were collected from Hong Kong for PCBs analyses. Total PCBs concentrations ranged from 46.8 to 249ngg-1, with a median of 107ngg-1. Manufacturing plant showed the highest concentration among all of sampling sites. PCB 77 was found as the dominant congeners. The bioaccessibility of PCBs in small intestinal juice ranging from 8.3% to 26.0% was significantly higher than that in gastric condition, ranging from 4.8% to 12.4%. In addition, significant negative correlations (p<0.05) were observed between KOW and bioaccessibility for all workplace dust samples. Risk assessment indicated that the averaged daily dose of dioxin-like PCBs via non-dietary intake of workplace dust, considering the bioaccessibility of PCBs, were much lower than the TDI of dioxins (2.3pg WHO-TEQ kgbw-1d-1) established by Joint FAO/WHO Expert Committee on Food Additives.

AB - Human exposure to bioaccessible PCBs via indoor dust is limited around the world. In the present study, the workplace dust sample from commercial office, hospital, secondary school, shopping mall, electronic factory and manufacturing plant were collected from Hong Kong for PCBs analyses. Total PCBs concentrations ranged from 46.8 to 249ngg-1, with a median of 107ngg-1. Manufacturing plant showed the highest concentration among all of sampling sites. PCB 77 was found as the dominant congeners. The bioaccessibility of PCBs in small intestinal juice ranging from 8.3% to 26.0% was significantly higher than that in gastric condition, ranging from 4.8% to 12.4%. In addition, significant negative correlations (p<0.05) were observed between KOW and bioaccessibility for all workplace dust samples. Risk assessment indicated that the averaged daily dose of dioxin-like PCBs via non-dietary intake of workplace dust, considering the bioaccessibility of PCBs, were much lower than the TDI of dioxins (2.3pg WHO-TEQ kgbw-1d-1) established by Joint FAO/WHO Expert Committee on Food Additives.

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Bioaccessibility of polychlorinated biphenyls in workplace dust and its implication for risk assessment

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