Bicyclic polyketide lactones from Chinese medicinal ants, Polyrhacis lamellidens

Zhi Hong JIANG*, Qing Xiong Yang, Takashi Tanaka, Isao Kouno

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

30 Citations (Scopus)


Two new bicyclic polyketide lactones, polyrhacitides A (1) and B (2), were isolated from Chinese medicinal ants, Polyrhacis lamellidens, which have been used as an effective therapeutic agent to treat rheumatoid arthritis and hepatitis in China. Their absolute structures were elucidated on the basis of spectroscopic analyses and chemical evidence. The occurrence of polyketides with similar structures in plants of the Lamiaceae, Lauraceae, and Staphyleaceae indicates their significance in the study of chemical ecology.

Original languageEnglish
Pages (from-to)724-727
Number of pages4
JournalJournal of Natural Products
Issue number4
Publication statusPublished - Apr 2008

Scopus Subject Areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry


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