TY - JOUR
T1 - Associations between qi stagnation constitution, suboptimal health status, and lifestyle factors in southern China
T2 - A population-based cross-sectional study
AU - Zhang, Haiyun
AU - Chen, Jieyu
AU - Chen, Jieling
AU - Liu, Yangzhi
AU - Yu, Jiahui
AU - Wang, Ji
AU - Zhou, Yumei
AU - Yu, Longmei
AU - Kwan, Hiu Yee
AU - Zhao, Xiaoshan
N1 - Funding information:
This study was supported by the National Natural Science Foundation of China (T2341019), NSFC-Guangdong Joint Fund (U1132001), General Program of the National Natural Science Foundation of China (82174243 and 82204948), Natural Science Foundation of Guangdong Province, China (2023A1515110757), Guangzhou Science and Technology Plan Project (2024B03J1343), Major Scientific and Technological Project of Guangzhou Municipal Health Commission (20252D003), Research Project of Traditional Chinese Medicine Bureau of Guangdong Province (20241208), General project of Beijing Natural Science Foundation (7242227), Fundamental Research Funds for the Central Universities (BZY-JMZY-2022-001 and 2023-JYB-JBZD-009), High-level Key Discipline of the National Administration of Traditional Chinese Medicine-Traditional Chinese Constitutional Medicine (zyyzdxk-2023251), Major Science and Technology Special Projects in Hubei Province (2023BCA005), and the Chief Scientist Research Project of Hubei Shizhen Laboratory (HSL2024SX0002).
Publisher Copyright:
© 2025 Published by Elsevier B.V. on behalf of Beijing University of Chinese Medicine.
PY - 2025/10
Y1 - 2025/10
N2 - Objective: To study the relationship between qi stagnation constitution and suboptimal health status (SHS) or lifestyle.Methods: From 2012 to 2013, we conducted a cross-sectional survey of 24 159 Chinese individuals aged 12–80 years. The qi stagnation constitution was assessed using the Constitution in Chinese Medicine Questionnaire. Health status was evaluated through medical records and the Subhealth Measurement Scale V1.0 (SHMS V1.0). Health-promoting lifestyles were measured using the Health-Promoting Lifestyle Profile II (HPLP-II).Results: Of the 24 159 participants, 16.1% and 15.2% were classified as “always” and “sometimes” having the qi stagnation constitution, respectively. Those classified as “rarely” having the qi stagnation constitution scored higher on both the HPLP-II and SHMS V1.0. The participants classified as “always” having the qi stagnation constitution showed a significant association with SHS or disease compared to other imbalanced constitutions. Those in the “always” category were approximately 21 times more likely to be classified as having SHS (odds ratio [OR]: 21.17, 95% confidence interval [CI]: 15.74–28.45), whereas those in the “sometimes” category were approximately six times more likely (OR: 5.89, 95% CI: 5.04–6.90). Accordingly, the qi stagnation constitution score was significantly associated with the diagnosis of SHS, with an area under the curve of 0.77 (P < .001). A score of 18.75 yielded the highest Youden Index (0.407), with a sensitivity of 60.5% and a specificity of 80.3%. Significant associations were observed between health-promoting lifestyles and qi stagnation constitution severity in an ordinal regression analysis (P < .001). Protective factors included stress management (OR: 1.59), self-actualization (OR: 1.57), and exercise (OR: 1.36). In contrast, poorer interpersonal relationships (OR: 0.79), greater health responsibilities (OR: 0.86), and poorer nutrition (OR: 0.91) were associated with increased severity.Conclusion: Modulating the qi stagnation constitution through lifestyle interventions may help prevent the progression of SHS to disease, which aligns with core preventive principles in traditional Chinese medicine.
AB - Objective: To study the relationship between qi stagnation constitution and suboptimal health status (SHS) or lifestyle.Methods: From 2012 to 2013, we conducted a cross-sectional survey of 24 159 Chinese individuals aged 12–80 years. The qi stagnation constitution was assessed using the Constitution in Chinese Medicine Questionnaire. Health status was evaluated through medical records and the Subhealth Measurement Scale V1.0 (SHMS V1.0). Health-promoting lifestyles were measured using the Health-Promoting Lifestyle Profile II (HPLP-II).Results: Of the 24 159 participants, 16.1% and 15.2% were classified as “always” and “sometimes” having the qi stagnation constitution, respectively. Those classified as “rarely” having the qi stagnation constitution scored higher on both the HPLP-II and SHMS V1.0. The participants classified as “always” having the qi stagnation constitution showed a significant association with SHS or disease compared to other imbalanced constitutions. Those in the “always” category were approximately 21 times more likely to be classified as having SHS (odds ratio [OR]: 21.17, 95% confidence interval [CI]: 15.74–28.45), whereas those in the “sometimes” category were approximately six times more likely (OR: 5.89, 95% CI: 5.04–6.90). Accordingly, the qi stagnation constitution score was significantly associated with the diagnosis of SHS, with an area under the curve of 0.77 (P < .001). A score of 18.75 yielded the highest Youden Index (0.407), with a sensitivity of 60.5% and a specificity of 80.3%. Significant associations were observed between health-promoting lifestyles and qi stagnation constitution severity in an ordinal regression analysis (P < .001). Protective factors included stress management (OR: 1.59), self-actualization (OR: 1.57), and exercise (OR: 1.36). In contrast, poorer interpersonal relationships (OR: 0.79), greater health responsibilities (OR: 0.86), and poorer nutrition (OR: 0.91) were associated with increased severity.Conclusion: Modulating the qi stagnation constitution through lifestyle interventions may help prevent the progression of SHS to disease, which aligns with core preventive principles in traditional Chinese medicine.
KW - Cross-sectional study
KW - Health-promoting lifestyle
KW - Qi stagnation constitution
KW - Suboptimal health status
KW - Traditional Chinese medicine constitution
UR - https://www.scopus.com/pages/publications/105017579785
U2 - 10.1016/j.jtcms.2025.09.002
DO - 10.1016/j.jtcms.2025.09.002
M3 - Journal article
AN - SCOPUS:105017579785
SN - 2095-7548
VL - 12
SP - 521
EP - 530
JO - Journal of Traditional Chinese Medical Sciences
JF - Journal of Traditional Chinese Medical Sciences
IS - 4
ER -