Assignments of 1H and 13C NMR signals of Euphorbia factor L1 and investigation of its anticancer activity in vitro

Jian Ye Zhang; Chao Zhang; Hubiao Chen; Li Wu Fu; Yi Wen Tao; Xiao Qiong Zheng; Zhi Min Cao; Yue Fei Zhong; Li Hong Yu

Assignments of ¹H and ¹³C NMR signals of Euphorbia factor L1 and investigation of its anticancer activity in vitro

Jian Ye Zhang^*, Chao Zhang, Hubiao Chen, Li Wu Fu, Yi Wen Tao, Xiao Qiong Zheng, Zhi Min Cao, Yue Fei Zhong, Li Hong Yu

^*Corresponding author for this work

School of Chinese Medicine

Research output: Contribution to journal › Journal article › peer-review

15 Citations (Scopus)

Abstract

In this article, we reported the isolation and characterization of Euphorbia factor L1 from Caper Euphorbia seed. The complete ¹H and ¹³C NMR signals were assigned with the help of 1D, 2D NMR techniques. In addition, the anticancer activities of Euphorbia factor L1 were investigated. It exhibited potent cytotoxicity to KB, KBv200, MCF-7 and MCF-7/ADR cells with the IC ₅₀ values of 30.83 ± 2.93, 28.11 ± 3.08, 39.47 ± 4.03 and 42.69 ± 4.27 μg/ml, respectively.

Original language	English
Pages (from-to)	335-338
Number of pages	4
Journal	Journal of Medicinal Plants Research
Volume	4
Issue number	4
Publication status	Published - 18 Feb 2010

User-Defined Keywords

Anticancer activity
Caper euphorbia seed
NMR signals

Cite this

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title = "Assignments of 1H and 13C NMR signals of Euphorbia factor L1 and investigation of its anticancer activity in vitro",

abstract = "In this article, we reported the isolation and characterization of Euphorbia factor L1 from Caper Euphorbia seed. The complete 1H and 13C NMR signals were assigned with the help of 1D, 2D NMR techniques. In addition, the anticancer activities of Euphorbia factor L1 were investigated. It exhibited potent cytotoxicity to KB, KBv200, MCF-7 and MCF-7/ADR cells with the IC 50 values of 30.83 ± 2.93, 28.11 ± 3.08, 39.47 ± 4.03 and 42.69 ± 4.27 μg/ml, respectively.",

keywords = "Anticancer activity, Caper euphorbia seed, NMR signals",

author = "Zhang, {Jian Ye} and Chao Zhang and Hubiao Chen and Fu, {Li Wu} and Tao, {Yi Wen} and Zheng, {Xiao Qiong} and Cao, {Zhi Min} and Zhong, {Yue Fei} and Yu, {Li Hong}",

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T1 - Assignments of 1H and 13C NMR signals of Euphorbia factor L1 and investigation of its anticancer activity in vitro

AU - Zhang, Jian Ye

AU - Zhang, Chao

AU - Chen, Hubiao

AU - Fu, Li Wu

AU - Tao, Yi Wen

AU - Zheng, Xiao Qiong

AU - Cao, Zhi Min

AU - Zhong, Yue Fei

AU - Yu, Li Hong

PY - 2010/2/18

Y1 - 2010/2/18

N2 - In this article, we reported the isolation and characterization of Euphorbia factor L1 from Caper Euphorbia seed. The complete 1H and 13C NMR signals were assigned with the help of 1D, 2D NMR techniques. In addition, the anticancer activities of Euphorbia factor L1 were investigated. It exhibited potent cytotoxicity to KB, KBv200, MCF-7 and MCF-7/ADR cells with the IC 50 values of 30.83 ± 2.93, 28.11 ± 3.08, 39.47 ± 4.03 and 42.69 ± 4.27 μg/ml, respectively.

AB - In this article, we reported the isolation and characterization of Euphorbia factor L1 from Caper Euphorbia seed. The complete 1H and 13C NMR signals were assigned with the help of 1D, 2D NMR techniques. In addition, the anticancer activities of Euphorbia factor L1 were investigated. It exhibited potent cytotoxicity to KB, KBv200, MCF-7 and MCF-7/ADR cells with the IC 50 values of 30.83 ± 2.93, 28.11 ± 3.08, 39.47 ± 4.03 and 42.69 ± 4.27 μg/ml, respectively.

KW - Anticancer activity

KW - Caper euphorbia seed

KW - NMR signals

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M3 - Journal article

AN - SCOPUS:77949404364

SN - 1996-0875

VL - 4

SP - 335

EP - 338

JO - Journal of Medicinal Plants Research

JF - Journal of Medicinal Plants Research

IS - 4

ER -

Assignments of ¹H and ¹³C NMR signals of Euphorbia factor L1 and investigation of its anticancer activity in vitro

Abstract

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