Assignments of 1H and 13C NMR signals of Euphorbia factor L1 and investigation of its anticancer activity in vitro

Jian Ye Zhang*, Chao Zhang, Hubiao CHEN, Li Wu Fu, Yi Wen Tao, Xiao Qiong Zheng, Zhi Min Cao, Yue Fei Zhong, Li Hong Yu

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

In this article, we reported the isolation and characterization of Euphorbia factor L1 from Caper Euphorbia seed. The complete 1H and 13C NMR signals were assigned with the help of 1D, 2D NMR techniques. In addition, the anticancer activities of Euphorbia factor L1 were investigated. It exhibited potent cytotoxicity to KB, KBv200, MCF-7 and MCF-7/ADR cells with the IC 50 values of 30.83 ± 2.93, 28.11 ± 3.08, 39.47 ± 4.03 and 42.69 ± 4.27 μg/ml, respectively.

Original languageEnglish
Pages (from-to)335-338
Number of pages4
JournalJournal of Medicinal Plants Research
Volume4
Issue number4
Publication statusPublished - 18 Feb 2010

Scopus Subject Areas

  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Plant Science
  • Complementary and alternative medicine

User-Defined Keywords

  • Anticancer activity
  • Caper euphorbia seed
  • NMR signals

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