Assessment of risk to humans of bisphenol A in marine and freshwater fish from Pearl River Delta, China

Xi WEI, Yeqing Huang, Ming Hung WONG, John P. Giesy, Chris K C WONG*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

76 Citations (Scopus)


Bisphenol A (BPA) is a high production-volume chemical used in the manufacture of a wide variety of consumer products. However it is also a ubiquitous contaminant that can interfere with endocrine systems of wildlife and humans. China is the " world factory" and the Pearl River Delta is the major manufacturing center and is consequently polluted. Concentrations of BPA in meats of marketable fish had not been previously reported for this region. In the study upon which we report here concentrations of BPA were determined in 20 common species of freshwater and marine fish, collected from markets in Hong Kong, SAR, China. A comprehensive analytical method based on SPE extraction and liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) was developed, validated and applied. The method limit of detection (LOD) and limit of quantification (LOQ) were 0.5 and 1.25ngg-1dw, respectively. BPA was detected in 19 species of fish at concentrations, ranging from 0.5 to 2.0ngg-1ww. Average daily BPA intake per person ranged from 1.1×102ngd-1 for marine fish and 2.2×102ngd-1 for freshwater fish. Concentrations of BPA in fish from Hong Kong markets unlikely would be causing adverse population-level effects in humans.

Original languageEnglish
Pages (from-to)122-128
Number of pages7
Issue number1
Publication statusPublished - Sept 2011

Scopus Subject Areas

  • Environmental Engineering
  • Environmental Chemistry
  • Chemistry(all)
  • Pollution
  • Health, Toxicology and Mutagenesis

User-Defined Keywords

  • Bisphenol A
  • Fish pollution
  • Health
  • LC/MS/MS


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