Assessment of risk to humans of bisphenol A in marine and freshwater fish from Pearl River Delta, China

Xi Wei; Yeqing Huang; Ming H. Wong; John P. Giesy; Chris K.C. Wong

doi:10.1016/j.chemosphere.2011.05.038

Assessment of risk to humans of bisphenol A in marine and freshwater fish from Pearl River Delta, China

Xi Wei, Yeqing Huang, Ming H. Wong, John P. Giesy, Chris K.C. Wong^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › peer-review

79 Citations (Scopus)

Abstract

Bisphenol A (BPA) is a high production-volume chemical used in the manufacture of a wide variety of consumer products. However it is also a ubiquitous contaminant that can interfere with endocrine systems of wildlife and humans. China is the " world factory" and the Pearl River Delta is the major manufacturing center and is consequently polluted. Concentrations of BPA in meats of marketable fish had not been previously reported for this region. In the study upon which we report here concentrations of BPA were determined in 20 common species of freshwater and marine fish, collected from markets in Hong Kong, SAR, China. A comprehensive analytical method based on SPE extraction and liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) was developed, validated and applied. The method limit of detection (LOD) and limit of quantification (LOQ) were 0.5 and 1.25ngg^-1dw, respectively. BPA was detected in 19 species of fish at concentrations, ranging from 0.5 to 2.0ngg^-1ww. Average daily BPA intake per person ranged from 1.1×10²ngd^-1 for marine fish and 2.2×10²ngd^-1 for freshwater fish. Concentrations of BPA in fish from Hong Kong markets unlikely would be causing adverse population-level effects in humans.

Original language	English
Pages (from-to)	122-128
Number of pages	7
Journal	Chemosphere
Volume	85
Issue number	1
DOIs	https://doi.org/10.1016/j.chemosphere.2011.05.038
Publication status	Published - Sept 2011

Scopus Subject Areas

Environmental Engineering
Environmental Chemistry
General Chemistry
Pollution
Health, Toxicology and Mutagenesis

User-Defined Keywords

Bisphenol A
Fish pollution
Health
LC/MS/MS

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.chemosphere.2011.05.038

Cite this

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title = "Assessment of risk to humans of bisphenol A in marine and freshwater fish from Pearl River Delta, China",

abstract = "Bisphenol A (BPA) is a high production-volume chemical used in the manufacture of a wide variety of consumer products. However it is also a ubiquitous contaminant that can interfere with endocrine systems of wildlife and humans. China is the {"} world factory{"} and the Pearl River Delta is the major manufacturing center and is consequently polluted. Concentrations of BPA in meats of marketable fish had not been previously reported for this region. In the study upon which we report here concentrations of BPA were determined in 20 common species of freshwater and marine fish, collected from markets in Hong Kong, SAR, China. A comprehensive analytical method based on SPE extraction and liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) was developed, validated and applied. The method limit of detection (LOD) and limit of quantification (LOQ) were 0.5 and 1.25ngg-1dw, respectively. BPA was detected in 19 species of fish at concentrations, ranging from 0.5 to 2.0ngg-1ww. Average daily BPA intake per person ranged from 1.1×102ngd-1 for marine fish and 2.2×102ngd-1 for freshwater fish. Concentrations of BPA in fish from Hong Kong markets unlikely would be causing adverse population-level effects in humans.",

keywords = "Bisphenol A, Fish pollution, Health, LC/MS/MS",

author = "Xi Wei and Yeqing Huang and Wong, {Ming H.} and Giesy, {John P.} and Wong, {Chris K.C.}",

note = "Funding Information: This work was supported by the Super Faculty Research Grant, Hong Kong Baptist University and Collaborative Research Fund (HKBU 1/CRF/08 to Prof. C.K.C. Wong) University Grants Committee. Prof. Giesy was supported by the Canada Research Chair program and an at large Chair Professorship at the Department of Biology and Chemistry and State Key Laboratory in Marine Pollution, City University of Hong Kong.",

year = "2011",

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AU - Wei, Xi

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AU - Giesy, John P.

AU - Wong, Chris K.C.

N1 - Funding Information: This work was supported by the Super Faculty Research Grant, Hong Kong Baptist University and Collaborative Research Fund (HKBU 1/CRF/08 to Prof. C.K.C. Wong) University Grants Committee. Prof. Giesy was supported by the Canada Research Chair program and an at large Chair Professorship at the Department of Biology and Chemistry and State Key Laboratory in Marine Pollution, City University of Hong Kong.

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N2 - Bisphenol A (BPA) is a high production-volume chemical used in the manufacture of a wide variety of consumer products. However it is also a ubiquitous contaminant that can interfere with endocrine systems of wildlife and humans. China is the " world factory" and the Pearl River Delta is the major manufacturing center and is consequently polluted. Concentrations of BPA in meats of marketable fish had not been previously reported for this region. In the study upon which we report here concentrations of BPA were determined in 20 common species of freshwater and marine fish, collected from markets in Hong Kong, SAR, China. A comprehensive analytical method based on SPE extraction and liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) was developed, validated and applied. The method limit of detection (LOD) and limit of quantification (LOQ) were 0.5 and 1.25ngg-1dw, respectively. BPA was detected in 19 species of fish at concentrations, ranging from 0.5 to 2.0ngg-1ww. Average daily BPA intake per person ranged from 1.1×102ngd-1 for marine fish and 2.2×102ngd-1 for freshwater fish. Concentrations of BPA in fish from Hong Kong markets unlikely would be causing adverse population-level effects in humans.

AB - Bisphenol A (BPA) is a high production-volume chemical used in the manufacture of a wide variety of consumer products. However it is also a ubiquitous contaminant that can interfere with endocrine systems of wildlife and humans. China is the " world factory" and the Pearl River Delta is the major manufacturing center and is consequently polluted. Concentrations of BPA in meats of marketable fish had not been previously reported for this region. In the study upon which we report here concentrations of BPA were determined in 20 common species of freshwater and marine fish, collected from markets in Hong Kong, SAR, China. A comprehensive analytical method based on SPE extraction and liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) was developed, validated and applied. The method limit of detection (LOD) and limit of quantification (LOQ) were 0.5 and 1.25ngg-1dw, respectively. BPA was detected in 19 species of fish at concentrations, ranging from 0.5 to 2.0ngg-1ww. Average daily BPA intake per person ranged from 1.1×102ngd-1 for marine fish and 2.2×102ngd-1 for freshwater fish. Concentrations of BPA in fish from Hong Kong markets unlikely would be causing adverse population-level effects in humans.

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Assessment of risk to humans of bisphenol A in marine and freshwater fish from Pearl River Delta, China

Abstract

Scopus Subject Areas

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UN SDGs

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