AptGEN: Rapid Discovery of AI-Generated Aptamers Targeting CTGF CT-domain for DMD Fibrosis

Xin Yang; Shanshan Yao; Meishen Ren; Huarui Zhang; Sifan Yu; Shijian Ding; Yufei Pan; Xiaohui Tao; Hewen Jiang; Ning Zhang; Luyao Wang; Yuan Ma; Wei Kang; Aiping Lyu; Yixin He; Zongkang Zhang; Yuanyuan Yu; Baoting Zhang; Ge Zhang

doi:10.1093/jbmr/zjaf166

AptGEN: Rapid Discovery of AI-Generated Aptamers Targeting CTGF CT-domain for DMD Fibrosis

Xin Yang
, Shanshan Yao
, Meishen Ren
, Huarui Zhang
, Sifan Yu
, Shijian Ding
, Yufei Pan
, Xiaohui Tao
, Hewen Jiang
, Ning Zhang
, Luyao Wang
, Yuan Ma
, Wei Kang
, Aiping Lyu
, Yixin He
, Zongkang Zhang
, Yuanyuan Yu
, Baoting Zhang
, Ge Zhang

Research output: Contribution to journal › Conference article › peer-review

Original language	English
Pages (from-to)	94
Number of pages	1
Journal	Journal of Bone and Mineral Research
Volume	40
Issue number	Supplement 1
DOIs	https://doi.org/10.1093/jbmr/zjaf166
Publication status	Published - 17 Nov 2025
Event	2025 Annual Meeting of the American Society for Bone and Mineral Research, ASBMR 2025 - Seattle, United States Duration: 5 Sept 2025 → 8 Sept 2025 https://academic.oup.com/jbmr/article/40/Supplement_1/i1/8325053 (Conference abstract)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1093/jbmr/zjaf166

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Yang, X., Yao, S., Ren, M., Zhang, H., Yu, S., Ding, S., Pan, Y., Tao, X., Jiang, H., Zhang, N., Wang, L., Ma, Y., Kang, W., Lyu, A., He, Y., Zhang, Z., Yu, Y., Zhang, B., & Zhang, G. (2025). AptGEN: Rapid Discovery of AI-Generated Aptamers Targeting CTGF CT-domain for DMD Fibrosis. Journal of Bone and Mineral Research, 40(Supplement 1), 94. https://doi.org/10.1093/jbmr/zjaf166

@article{51d5f90e74424872a5fefab3a09cf0e9,

title = "AptGEN: Rapid Discovery of AI-Generated Aptamers Targeting CTGF CT-domain for DMD Fibrosis",

author = "Xin Yang and Shanshan Yao and Meishen Ren and Huarui Zhang and Sifan Yu and Shijian Ding and Yufei Pan and Xiaohui Tao and Hewen Jiang and Ning Zhang and Luyao Wang and Yuan Ma and Wei Kang and Aiping Lyu and Yixin He and Zongkang Zhang and Yuanyuan Yu and Baoting Zhang and Ge Zhang",

year = "2025",

month = nov,

day = "17",

doi = "10.1093/jbmr/zjaf166",

language = "English",

volume = "40",

pages = "94",

journal = "Journal of Bone and Mineral Research",

issn = "0884-0431",

publisher = "Oxford University Press",

number = "Supplement 1",

note = "2025 Annual Meeting of the American Society for Bone and Mineral Research, ASBMR 2025 ; Conference date: 05-09-2025 Through 08-09-2025",

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}

Yang, X, Yao, S, Ren, M, Zhang, H, Yu, S, Ding, S, Pan, Y, Tao, X, Jiang, H, Zhang, N, Wang, L, Ma, Y, Kang, W, Lyu, A, He, Y, Zhang, Z, Yu, Y, Zhang, B & Zhang, G 2025, 'AptGEN: Rapid Discovery of AI-Generated Aptamers Targeting CTGF CT-domain for DMD Fibrosis', Journal of Bone and Mineral Research, vol. 40, no. Supplement 1, pp. 94. https://doi.org/10.1093/jbmr/zjaf166

TY - JOUR

T1 - AptGEN

T2 - 2025 Annual Meeting of the American Society for Bone and Mineral Research, ASBMR 2025

AU - Yang, Xin

AU - Yao, Shanshan

AU - Ren, Meishen

AU - Zhang, Huarui

AU - Yu, Sifan

AU - Ding, Shijian

AU - Pan, Yufei

AU - Tao, Xiaohui

AU - Jiang, Hewen

AU - Zhang, Ning

AU - Wang, Luyao

AU - Ma, Yuan

AU - Kang, Wei

AU - Lyu, Aiping

AU - He, Yixin

AU - Zhang, Zongkang

AU - Yu, Yuanyuan

AU - Zhang, Baoting

AU - Zhang, Ge

PY - 2025/11/17

Y1 - 2025/11/17

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U2 - 10.1093/jbmr/zjaf166

DO - 10.1093/jbmr/zjaf166

M3 - Conference article

SN - 0884-0431

VL - 40

SP - 94

JO - Journal of Bone and Mineral Research

JF - Journal of Bone and Mineral Research

IS - Supplement 1

Y2 - 5 September 2025 through 8 September 2025

ER -

AptGEN: Rapid Discovery of AI-Generated Aptamers Targeting CTGF CT-domain for DMD Fibrosis

UN SDGs

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