Apoptosis and anti-cancer drug discovery: The power of medicinal fungi and plants

Jack Ho Wong*, Stephen Cho Wing Sze*, Tzi Bun Ng*, Randy Chi Fai Cheung, Chit Tam*, Kalin Yanbo Zhang*, Xiuli Dan, Yau Sang Chan, William Chi Shing Cho, Charlene Cheuk Wing Ng, Mary Miu Yee Waye, Weicheng Liang, Jinfang Zhang, Jie Yang, Xiuyun Ye, Juan Lin, Xiujuan Ye*, Hexiang Wang, Fang Liu, David Wai Chan*Hextan Yuen Sheung Ngan*, Ou Sha*, Guohui Li, Ryan Tse, Tak Fu Tse*, Helen Chan*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

The purpose of this account is to review the compounds capable of eliciting mitochondria-mediated apoptosis in cancer cells produced by medicinal fungi and plants. The medicinal fungi discussed encompass Cordyceps, Ganoderma species, Coriolus versicolor and Hypsizygus marmoreus. The medicinal plants discussed comprise Astragalus complanatus, Dendrobium spp, Dioscorea spp, Glycyrrhiza spp, Panax notoginseng, Panax ginseng, and Momordica charantia. These compounds have the potential of development into anticancer drugs.
Original languageEnglish
Pages (from-to)5613-5630
Number of pages18
JournalCurrent Medicinal Chemistry
Volume25
Issue number40
DOIs
Publication statusPublished - Dec 2018
Externally publishedYes

Scopus Subject Areas

  • Medicine(all)

User-Defined Keywords

  • Medicinal fungi
  • medicinal plants
  • anticancer
  • apoptosis
  • mitochondria

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