Antituberculosis cycloartane triterpenoids from Radermachera boniana

Ngan B. Truong, Cuong V. Pham*, Huong T.M. Doan, Hung V. Nguyen, Cuong M. Nguyen, Hiep T. Nguyen, Hong Jie Zhang, Harry H.S. Fong, Scott G. Franzblau, Djaja D. Soejarto, Minh V. Chau*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

38 Citations (Scopus)

Abstract

Three new triterpenoids, bonianic acids A (1) and B (2) and 3-O-acetyluncaric acid (3), were isolated from the leaves and twigs of Radermachera boniana, together with six known compounds, ursolic acid (4), oleanolic acid (5), 3-epi-oleanolic acid (6), 3α-O-acetyl-α- boswellic acid (7), ergosterol peroxide (8), and β-sitostenone (9). Ergosterol peroxide (8) and bonianic acids A (1) and B (2) exhibited significant activity against Mycobacterium tuberculosis H37Rv strain. (Chemical Equation Presented).

Original languageEnglish
Pages (from-to)1318-1322
Number of pages5
JournalJournal of Natural Products
Volume74
Issue number5
Early online date6 Apr 2011
DOIs
Publication statusPublished - 27 May 2011

Scopus Subject Areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Antituberculosis cycloartane triterpenoids from Radermachera boniana'. Together they form a unique fingerprint.

Cite this