Antimicrobial anthraquinones from Morinda angustifolia

Wei Xiang; Qi-Shi Song; Hong-Jie Zhang; Shi-Ping Guo

doi:10.1016/j.fitote.2008.04.008

Antimicrobial anthraquinones from Morinda angustifolia

Wei Xiang^*
, Qi-Shi Song
, Hong-Jie Zhang
, Shi-Ping Guo

^*Corresponding author for this work

Chinese Medicine - Teaching and Research Division

Research output: Contribution to journal › Journal article › peer-review

63 Citations (Scopus)

Abstract

Investigation on Morinda angustifolia resulted in the isolation of a new anthraquinone, 1,8-dihydroxy-2-methyl-3,7-dimethoxyanthraquinone (1), along with five known analogues, lucidin 3-O-β-primeveroside (2), 1,3-dihydroxy-2-methylanthraquinone (3), lucidin- ω -ethyl ether (4), lucidin-ω-butyl ether (5) and damnacanthol (6). The new compound demonstrated significant antimicrobial activity against Bacillus subtilis, Escherichia coli, Micrococcus luteus, Sarcina lutea, Candida albicans and Saccharomyces sake.

Original language	English
Pages (from-to)	501-504
Number of pages	4
Journal	Fitoterapia
Volume	79
Issue number	7-8
DOIs	https://doi.org/10.1016/j.fitote.2008.04.008
Publication status	Published - Dec 2008

User-Defined Keywords

1,8-Dihydroxy-2-methyl-3,7-dimethoxyanthraquinone
Anthraquinones
Antimicrobial activitis
Morinda angustifolia

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10.1016/j.fitote.2008.04.008

Cite this

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title = "Antimicrobial anthraquinones from Morinda angustifolia",

abstract = "Investigation on Morinda angustifolia resulted in the isolation of a new anthraquinone, 1,8-dihydroxy-2-methyl-3,7-dimethoxyanthraquinone (1), along with five known analogues, lucidin 3-O-β-primeveroside (2), 1,3-dihydroxy-2-methylanthraquinone (3), lucidin- ω -ethyl ether (4), lucidin-ω-butyl ether (5) and damnacanthol (6). The new compound demonstrated significant antimicrobial activity against Bacillus subtilis, Escherichia coli, Micrococcus luteus, Sarcina lutea, Candida albicans and Saccharomyces sake.",

keywords = "1,8-Dihydroxy-2-methyl-3,7-dimethoxyanthraquinone, Anthraquinones, Antimicrobial activitis, Morinda angustifolia",

author = "Wei Xiang and Qi-Shi Song and Hong-Jie Zhang and Shi-Ping Guo",

year = "2008",

month = dec,

doi = "10.1016/j.fitote.2008.04.008",

language = "English",

volume = "79",

pages = "501--504",

journal = "Fitoterapia",

issn = "0367-326X",

publisher = "Elsevier B.V.",

number = "7-8",

}

TY - JOUR

T1 - Antimicrobial anthraquinones from Morinda angustifolia

AU - Xiang, Wei

AU - Song, Qi-Shi

AU - Zhang, Hong-Jie

AU - Guo, Shi-Ping

PY - 2008/12

Y1 - 2008/12

N2 - Investigation on Morinda angustifolia resulted in the isolation of a new anthraquinone, 1,8-dihydroxy-2-methyl-3,7-dimethoxyanthraquinone (1), along with five known analogues, lucidin 3-O-β-primeveroside (2), 1,3-dihydroxy-2-methylanthraquinone (3), lucidin- ω -ethyl ether (4), lucidin-ω-butyl ether (5) and damnacanthol (6). The new compound demonstrated significant antimicrobial activity against Bacillus subtilis, Escherichia coli, Micrococcus luteus, Sarcina lutea, Candida albicans and Saccharomyces sake.

AB - Investigation on Morinda angustifolia resulted in the isolation of a new anthraquinone, 1,8-dihydroxy-2-methyl-3,7-dimethoxyanthraquinone (1), along with five known analogues, lucidin 3-O-β-primeveroside (2), 1,3-dihydroxy-2-methylanthraquinone (3), lucidin- ω -ethyl ether (4), lucidin-ω-butyl ether (5) and damnacanthol (6). The new compound demonstrated significant antimicrobial activity against Bacillus subtilis, Escherichia coli, Micrococcus luteus, Sarcina lutea, Candida albicans and Saccharomyces sake.

KW - 1,8-Dihydroxy-2-methyl-3,7-dimethoxyanthraquinone

KW - Anthraquinones

KW - Antimicrobial activitis

KW - Morinda angustifolia

U2 - 10.1016/j.fitote.2008.04.008

DO - 10.1016/j.fitote.2008.04.008

M3 - Journal article

SN - 0367-326X

VL - 79

SP - 501

EP - 504

JO - Fitoterapia

JF - Fitoterapia

IS - 7-8

ER -

Antimicrobial anthraquinones from Morinda angustifolia

Abstract

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