Analysis of tire wear-derived toxic organic substances and associated toxicological implications by mass spectrometry: Recent advances

Congcong Pei, Shijiao Hou, Zifang Peng, Xu Zhang, Dan Yin, Wenfen Zhang, Yanhao Zhang*, Zongwei Cai, Shusheng Zhang

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Tire wear-derived toxic organic substances (TWTOSs), as broadly distributed and poisonous contaminants, have threatened the safety of the environment, food, and organisms. Accurate, sensitive, and rapid detection of TWTOSs is essential for understanding their occurrence, environmental fate, and biotoxicities. Mass spectrometry (MS) has been increasingly employed for identification, quantification, and toxicity tracking of emerging pollutants in terms of high sensitivity/throughput and easy operation. Herein, we reviewed the recent advances of MS technology for detecting TWTOSs (e.g., cyclic amines and benzotriazoles/benzothiazoles) in the ecosystem and food/biological samples, and assessing the toxicological implications of TWTOSs on the organism. A comprehensive update on the MS-based detection of TWTOSs and the exposure risks’ evaluation will be provided in this review, highlighting the necessity of innovation of analytical technology for environmental and public health safety.

Original languageEnglish
Article number118059
Number of pages15
JournalTrAC - Trends in Analytical Chemistry
Volume182
DOIs
Publication statusPublished - Jan 2025

Scopus Subject Areas

  • Analytical Chemistry
  • Spectroscopy

User-Defined Keywords

  • Environmental occurrence
  • Mass spectrometry
  • Tire wear-derived toxic organic substances
  • Toxicity

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