An oligonucleotide-based label-free luminescent switch-on probe for RNA detection utilizing a G-quadruplex-selective iridium(iii) complex

Edmond Dik Lung MA; Sheng Lin; Ka Ho Leung; Hai Jing Zhong; Li Juan Liu; Daniel Shiu Hin Chan; Anne Bourdoncle; Jean Louis Mergny; Hui Min David Wang; Chung Hang Leung

doi:10.1039/c4nr00541d

An oligonucleotide-based label-free luminescent switch-on probe for RNA detection utilizing a G-quadruplex-selective iridium(iii) complex

Edmond Dik Lung MA^*, Sheng Lin, Ka Ho Leung, Hai Jing Zhong, Li Juan Liu, Daniel Shiu Hin Chan, Anne Bourdoncle, Jean Louis Mergny, Hui Min David Wang, Chung Hang Leung

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

56 Citations (Scopus)

Abstract

We report herein the synthesis and application of a novel G-quadruplex-selective luminescent iridium(iii) complex for the construction of an oligonucleotide-based, label-free, rapid and convenient luminescent RNA detection platform. This journal is

Original language	English
Pages (from-to)	8489-8494
Number of pages	6
Journal	Nanoscale
Volume	6
Issue number	15
DOIs	https://doi.org/10.1039/c4nr00541d
Publication status	Published - 7 Aug 2014

Scopus Subject Areas

Materials Science(all)

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10.1039/c4nr00541d

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abstract = "We report herein the synthesis and application of a novel G-quadruplex-selective luminescent iridium(iii) complex for the construction of an oligonucleotide-based, label-free, rapid and convenient luminescent RNA detection platform. This journal is",

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AU - MA, Edmond Dik Lung

AU - Lin, Sheng

AU - Leung, Ka Ho

AU - Zhong, Hai Jing

AU - Liu, Li Juan

AU - Chan, Daniel Shiu Hin

AU - Bourdoncle, Anne

AU - Mergny, Jean Louis

AU - Wang, Hui Min David

AU - Leung, Chung Hang

PY - 2014/8/7

Y1 - 2014/8/7

N2 - We report herein the synthesis and application of a novel G-quadruplex-selective luminescent iridium(iii) complex for the construction of an oligonucleotide-based, label-free, rapid and convenient luminescent RNA detection platform. This journal is

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M3 - Journal article

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SN - 2040-3364

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JO - Nanoscale

JF - Nanoscale

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An oligonucleotide-based label-free luminescent switch-on probe for RNA detection utilizing a G-quadruplex-selective iridium(iii) complex

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