An Ir(III) complex chemosensor for the detection of thiols

Zhifeng Mao, Jinbiao Liu, Tian Shu Kang, Wanhe Wang, Simon Q B HAN, Chun Ming Wang, Chung Hang Leung, Edmond Dik Lung MA*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

In this study, we report the use of a cyclometalated luminescent iridium(III) complex for the visualization of thiols. The detection of glutathione (GSH) by complex 1 is achieved through the reduction of its phendione N^N donor, which influences the metal-to-ligand charge-transfer (MLCT) of the complex. Complex 1 produced a maximum threefold luminescence enhancement at 587 nm in response to GSH. The linear detection range of 1 for GSH is between 0.2 and 2 M equivalents of GSH, with a detection limit of 1.67 μM. Complex 1 also displays good selectivity for thiols over other amino acids.

Original languageEnglish
Pages (from-to)109-114
Number of pages6
JournalScience and Technology of Advanced Materials
Volume17
Issue number1
DOIs
Publication statusPublished - 2016

Scopus Subject Areas

  • Materials Science(all)

User-Defined Keywords

  • Chemosensor
  • Iridium(III) complex
  • Thiols

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