@article{f1beba0982924e9ca0b90c4c538a0725,
title = "An iridium(III) complex/G-quadruplex ensemble for detection of ochratoxin A based on long-lifetime luminescent",
abstract = "A G-quadruplex-based platform has been developed for the time-resolved monitoring of ochratoxin A (OTA). The simple platform displays good sensitivity for OTA with a detection limit of 40 nM via steady-state emission spectroscopy. Notably, the platform showed a detection limit of 10.8 nM via time-resolved emission spectroscopy (TRES), which is about 4 times more sensitive than steady-state mode. Moreover, the probe showed excellent selectivity for OTA over other mycotoxins. Furthermore, OTA was successfully detected in actual herbal plant extracts samples. Our platform is the first to detect OTA using TRES to distinguish between the target signals versus the auto-fluorescence of real samples. This platform shows improved detection speed, accuracy and sensitivity with simple operation, low cost, and no requirement for complicated pre-processing.",
keywords = "G-quadruplex, Herbal plant extracts, OTA, TRES",
author = "Zhang, {Jia Tong} and Kang, {Tian Shu} and Wong, {Suk Yu} and Pei, {Ren Jun} and Ma, {Edmond Dik Lung} and Leung, {Chung Hang}",
note = "Funding Information: This work is supported by Hong Kong Baptist University (FRG2/17-18/003), Hong Kong; the Health and Medical Research Fund (HMRF/14150561), Hong Kong; National Natural Science Foundation of China (21575121, 21775131, 21628502), China; Hong Kong Baptist University Century Club Sponsorship Scheme 2018, Hong Kong; Interdisciplinary Research Matching Scheme (RC-IRMS/16-17/03), Hong Kong; Interdisciplinary Research Clusters Matching Scheme (RC-IRCs/17-18/03), Hong Kong; Matching Proof of Concept Fund (MPCF-001-2017/18), Hong Kong; Collaborative Research Fund (C5026-16G), Hong Kong; SKLEBA and HKBU Strategic Development Fund (SKLP_1718_P04), Hong Kong; the Science and Technology Development Fund, Macao SAR (077/2016/A2), Macao; the University of Macau (MYRG2018-00187-ICMS, MYRG2016-00151-ICMS-QRCM), Macao. Publisher copyright: {\textcopyright} 2019 Published by Elsevier Inc.",
year = "2019",
month = sep,
day = "1",
doi = "10.1016/j.ab.2019.06.005",
language = "English",
volume = "580",
pages = "49--55",
journal = "Analytical Biochemistry",
issn = "0003-2697",
publisher = "Academic Press Inc.",
}