TY - JOUR
T1 - An insight into anti-inflammatory effects of fungal beta-glucans
AU - Du, Bin
AU - Lin, Chengyuan
AU - BIAN, Zhaoxiang
AU - Xu, Baojun
N1 - Funding Information:
This project is jointly supported by Natural Science Foundation of Guangdong Province, China (Project Code: S2012010008961), and by Beijing Normal University-Hong Kong Baptist University United International College (grant number: UIC201329 ).
PY - 2015/1/1
Y1 - 2015/1/1
N2 - β-Glucans from fungi exhibit a broad spectrum of biological activities including anti-tumor, immune-modulating and anti-inflammatory properties. The anti-inflammatory effect is mediated through the regulation of various inflammatory cytokines, such as nitric oxide (NO), interleukins (ILs), tumor necrosis factor alpha (TNF)-α, interferon gamma (INF)-γ as well as non-cytokine mediator, prostaglandin E2 (PGE2). Up to now, the anti-inflammatory activity of β-glucans has received little attention. It is worthwhile to investigate the anti-inflammatory properties of fungal β-glucans in a separate review, discussing invitro studies, animal studies and human studies on anti-inflammation effects of fungal β-glucans, as well as the structure-anti-inflammatory activity relationships.
AB - β-Glucans from fungi exhibit a broad spectrum of biological activities including anti-tumor, immune-modulating and anti-inflammatory properties. The anti-inflammatory effect is mediated through the regulation of various inflammatory cytokines, such as nitric oxide (NO), interleukins (ILs), tumor necrosis factor alpha (TNF)-α, interferon gamma (INF)-γ as well as non-cytokine mediator, prostaglandin E2 (PGE2). Up to now, the anti-inflammatory activity of β-glucans has received little attention. It is worthwhile to investigate the anti-inflammatory properties of fungal β-glucans in a separate review, discussing invitro studies, animal studies and human studies on anti-inflammation effects of fungal β-glucans, as well as the structure-anti-inflammatory activity relationships.
UR - http://www.scopus.com/inward/record.url?scp=84919384281&partnerID=8YFLogxK
U2 - 10.1016/j.tifs.2014.09.002
DO - 10.1016/j.tifs.2014.09.002
M3 - Review article
AN - SCOPUS:84919384281
SN - 0924-2244
VL - 41
SP - 49
EP - 59
JO - Trends in Food Science and Technology
JF - Trends in Food Science and Technology
IS - 1
ER -