An approach to convert fragile hydrogel microfluidic chips into cartridges easy and reliable to use

Sin Yung Siu; Chiu Wing Chan; Yisu Wang; Langcheng Feng; Kangning Ren

An approach to convert fragile hydrogel microfluidic chips into cartridges easy and reliable to use

Sin Yung Siu
, Chiu Wing Chan
, Yisu Wang
, Langcheng Feng
, Kangning Ren^*

^*Corresponding author for this work

Department of Chemistry

Research output: Chapter in book/report/conference proceeding › Conference proceeding › peer-review

Abstract

A platform is created to convert fragile hydrogel microfluidic devices into standard cartridges that are easy and reliable to use. This platform avoids any stress to be applied to the hydrogel by fabricating it on a plastic support, and the employing of a leak-proof contactless interface further gets rid of the need to plug tubes. We demonstrate the application of this platform in rapid two-dimensional antimicrobial susceptibility testing, a first-ever highly-efficient method to assess the efficacy of drug combinations in treating drug-resistant bacteria. The platform is expected to be universally applicable to different scenes where hydrogel could be useful.

Original language	English
Title of host publication	MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publisher	Chemical and Biological Microsystems Society
Pages	947-948
Number of pages	2
ISBN (Electronic)	9781733419048
Publication status	Published - 23 Oct 2022
Event	26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022 - Hangzhou, China Duration: 23 Oct 2022 → 27 Oct 2022

Publication series

Name	MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference	26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022
Country/Territory	China
City	Hangzhou
Period	23/10/22 → 27/10/22

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 9 Industry, Innovation, and Infrastructure

User-Defined Keywords

antimicrobial resistance
cartridge
hydrogel
microfluidics

Cite this

Siu, S. Y., Chan, C. W., Wang, Y., Feng, L., & Ren, K. (2022). An approach to convert fragile hydrogel microfluidic chips into cartridges easy and reliable to use. In MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 947-948). (MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences). Chemical and Biological Microsystems Society.

Siu, Sin Yung ; Chan, Chiu Wing ; Wang, Yisu et al. / An approach to convert fragile hydrogel microfluidic chips into cartridges easy and reliable to use. MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2022. pp. 947-948 (MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

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title = "An approach to convert fragile hydrogel microfluidic chips into cartridges easy and reliable to use",

abstract = "A platform is created to convert fragile hydrogel microfluidic devices into standard cartridges that are easy and reliable to use. This platform avoids any stress to be applied to the hydrogel by fabricating it on a plastic support, and the employing of a leak-proof contactless interface further gets rid of the need to plug tubes. We demonstrate the application of this platform in rapid two-dimensional antimicrobial susceptibility testing, a first-ever highly-efficient method to assess the efficacy of drug combinations in treating drug-resistant bacteria. The platform is expected to be universally applicable to different scenes where hydrogel could be useful.",

keywords = "antimicrobial resistance, cartridge, hydrogel, microfluidics",

author = "Siu, \{Sin Yung\} and Chan, \{Chiu Wing\} and Yisu Wang and Langcheng Feng and Kangning Ren",

note = "Publisher Copyright: {\textcopyright} 2022 MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.; 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022 ; Conference date: 23-10-2022 Through 27-10-2022",

year = "2022",

month = oct,

day = "23",

language = "English",

series = "MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

publisher = "Chemical and Biological Microsystems Society",

pages = "947--948",

booktitle = "MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

}

Siu, SY, Chan, CW, Wang, Y, Feng, L & Ren, K 2022, An approach to convert fragile hydrogel microfluidic chips into cartridges easy and reliable to use. in MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences. MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Chemical and Biological Microsystems Society, pp. 947-948, 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022, Hangzhou, China, 23/10/22.

An approach to convert fragile hydrogel microfluidic chips into cartridges easy and reliable to use. / Siu, Sin Yung; Chan, Chiu Wing; Wang, Yisu et al.
MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2022. p. 947-948 (MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

Research output: Chapter in book/report/conference proceeding › Conference proceeding › peer-review

TY - GEN

T1 - An approach to convert fragile hydrogel microfluidic chips into cartridges easy and reliable to use

AU - Siu, Sin Yung

AU - Chan, Chiu Wing

AU - Wang, Yisu

AU - Feng, Langcheng

AU - Ren, Kangning

PY - 2022/10/23

Y1 - 2022/10/23

N2 - A platform is created to convert fragile hydrogel microfluidic devices into standard cartridges that are easy and reliable to use. This platform avoids any stress to be applied to the hydrogel by fabricating it on a plastic support, and the employing of a leak-proof contactless interface further gets rid of the need to plug tubes. We demonstrate the application of this platform in rapid two-dimensional antimicrobial susceptibility testing, a first-ever highly-efficient method to assess the efficacy of drug combinations in treating drug-resistant bacteria. The platform is expected to be universally applicable to different scenes where hydrogel could be useful.

AB - A platform is created to convert fragile hydrogel microfluidic devices into standard cartridges that are easy and reliable to use. This platform avoids any stress to be applied to the hydrogel by fabricating it on a plastic support, and the employing of a leak-proof contactless interface further gets rid of the need to plug tubes. We demonstrate the application of this platform in rapid two-dimensional antimicrobial susceptibility testing, a first-ever highly-efficient method to assess the efficacy of drug combinations in treating drug-resistant bacteria. The platform is expected to be universally applicable to different scenes where hydrogel could be useful.

KW - antimicrobial resistance

KW - cartridge

KW - hydrogel

KW - microfluidics

UR - https://www.scopus.com/pages/publications/85175689332

M3 - Conference proceeding

AN - SCOPUS:85175689332

T3 - MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences

SP - 947

EP - 948

BT - MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences

PB - Chemical and Biological Microsystems Society

T2 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022

Y2 - 23 October 2022 through 27 October 2022

ER -

Siu SY, Chan CW, Wang Y, Feng L, Ren K. An approach to convert fragile hydrogel microfluidic chips into cartridges easy and reliable to use. In MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society. 2022. p. 947-948. (MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

An approach to convert fragile hydrogel microfluidic chips into cartridges easy and reliable to use

Abstract

Publication series

Conference

UN SDGs

User-Defined Keywords

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Cite this