Keyphrases
Amyotrophic Lateral Sclerosis
100%
Nuclear Factor Erythroid 2-related Factor 2 (Nrf2)
100%
Selective Autophagy
100%
Anti-oxidative Stress
100%
Oxidative Stress Pathway
100%
SQSTM1
100%
Frontotemporal Lobar Degeneration
100%
NFE2L2
100%
Phosphorylation
33%
Autophagy
33%
TANK-binding Kinase 1 (TBK1)
33%
Autophagy Receptor
33%
Neurotoxicity
22%
Cargo
22%
Kelch-like ECH-associated Protein 1 (Keap1)
22%
Neurodegenerative Diseases
11%
Oxidative Stress
11%
Pathogenic Mechanism
11%
Disease-causing mutations
11%
Protein Aggregates
11%
Target Gene Expression
11%
Digestion
11%
Macroautophagy
11%
Autophagy Pathway
11%
Autophagosome
11%
Oxidative Stress Response
11%
Serine-threonine Kinase
11%
ULK1
11%
Dendrite Morphology
11%
TAR DNA-binding Protein 43 (TDP-43)
11%
Catabolic Pathway
11%
TARDBP
11%
Proteotoxic Stress
11%
Stress Granule Formation
11%
UBA Domain
11%
Cargo Binding
11%
Proteostasis
11%
Impaired Autophagy
11%
Biochemistry, Genetics and Molecular Biology
Oxidative Stress
100%
Autophagy
100%
Selective Autophagy
100%
NFE2L2
100%
Kinase
28%
Phosphotransferase
28%
KEAP1
28%
Gene Expression
14%
Serine
14%
Macroautophagy
14%
Threonine
14%
Autophagosome
14%
ULK1
14%
Transcription Factor Nrf2
14%
Transactive Response Dna Binding Protein-43
14%
TARDBP
14%
Protein Homeostasis
14%
Stress Granule
14%