Alboatisins A-C, ent-atisene diterpenoids from Isodon albopilosus

Sheng Xiong Huang, Yan Zhou, Li Bin Yang, Yong Zhao, Sheng Hong Li, Li Guang Lou, Quan Bin Han, Li Sheng Ding, Han Dong Sun*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

20 Citations (Scopus)


Three biogenetically interesting ent-kaurane-derived metabolites, alboatisins A-C (1-3), featuring a C-13-oxygenated ent-atisane skeleton, have been isolated from the aerial parts of Isodon albopilosus. Their structures were determined on the basis of spectroscopic evidence. Compound 2 exhibited cytotoxicity against A549 and HT-29 human cancer cells, with IC50 values of 8.3 and 7.9 μM, respectively.

Original languageEnglish
Pages (from-to)1053-1055
Number of pages3
JournalJournal of Natural Products
Issue number6
Early online date11 May 2007
Publication statusPublished - 1 Jun 2007

Scopus Subject Areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry


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