Advances and Applications in Organocatalytic Asymmetric aza-Michael Addition

Jun WANG, Pengfei Li*, Pui Ying Choy, Albert S. C. Chan, Fuk Yee Kwong

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

136 Citations (Scopus)

Abstract

Go forth and make bonds: The aza-Michael addition is an excellent way of forming CN bonds and is of tremendous significance in asymmetric synthesis. Recently, impressive progress has been achieved by employing new nitrogen nucleophiles, suitable acceptors, and more efficient catalyst systems for this important transformation. This review surveys the advances among intermolecular- and intramolecular aza-Michael addition and domino reactions involved aza-Michael addition developed between 2010 and early 2012.
Original languageEnglish
Pages (from-to)917-925
Number of pages9
JournalChemCatChem
Volume4
Issue number7
Early online date29 May 2012
DOIs
Publication statusPublished - Jul 2012

Scopus Subject Areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

User-Defined Keywords

  • Asymmetric synthesis
  • Brønsted catalysis
  • Michael addition
  • Organocatalysis

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