Adolescent exposure to micro/nanoplastics induces cognitive impairments in mice with neuronal morphological damage and multi-omic alterations

Keyphrases

• Polystyrene 100%
• Aged Mice 100%
• Cognitive Impairment 100%
• Multi-omics 100%
• Morphological Defects 100%
• Micro-nano Plastics 100%
• Adolescent Exposure 100%
• Metabolomics 50%
• Molecular Biology 50%
• Neurotoxicity 50%
• Gut Microbiota 50%
• Neurogenesis 50%
• Environmental Concern 50%
• Detrimental Effects 50%
• Neurotoxic Effects 50%
• PI3K-Akt Pathway 50%
• Western Blotting 50%
• Hippocampus 50%
• Strong Correlation 50%
• Toxicity Mechanism 50%
• Physiological Function 50%
• Gut Bacteria 50%
• Oral Exposure 50%
• Morris Water Maze 50%
• Multi-omics Analysis 50%
• Brain Function 50%
• Toxicological Potential 50%
• Toxicological Impacts 50%
• Y-maze Test 50%
• Neurobehavioral Function 50%
• Pollution Effects 50%
• Dendritic Spine Loss 50%
• Severe Cognitive Impairment 50%
• Hippocampal Transcriptome 50%
• Neuron Loss 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Cognitive Defect 100%
• Tamsulosin 100%
• Nanoplastics 100%
• Adolescent Exposure 100%
• Intestine Flora 66%
• Styrofoam 66%
• Transcriptome 33%
• Neurotoxicity 33%
• Western Blot 33%
• Protein Kinase B 33%

Neuroscience

• Cognitive Disorder 100%
• Tamsulosin 100%
• Western Blot 33%
• Neurotoxicity 33%
• Neurogenesis 33%
• Dendritic Spine 33%
• Hippocampus 33%
• Transcriptome 33%
• Protein Kinase B 33%
• Water Maze 33%
• Metabolome 33%
• Brain Function 33%
• Microflora 33%