TY - JOUR
T1 - A systematic review of the botanical, phytochemical and pharmacological profile of dracaena cochinchinensis, a plant source of the ethnomedicine dragon's blood
AU - Fan, Jia Yi
AU - Yi, Tao
AU - Sze-To, Chui Mei
AU - Zhu, Lin
AU - Peng, Wan Ling
AU - Zhang, Ya Zhou
AU - Zhao, Zhongzhen
AU - Chen, Hubiao
N1 - This research was funded by the Faculty Research Grant of Hong Kong Baptist University (FRG/08-09/II-52, FRG2/10-11/080)
PY - 2014/7
Y1 - 2014/7
N2 - "Dragon's blood" is the name given to a deep red resin obtained from a variety of plant sources. The resin extracted from stems of Dracaena cochinchinensis is one such source of "dragon's blood". It has a reputation for facilitating blood circulation and dispersing blood stasis. In traditional Chinese medicine, this resinous medicine is commonly prescribed to invigorate blood circulation for the treatment of traumatic injuries, blood stasis and pain. Modern pharmacological studies have found that this resinous medicine has anti-bacterial, anti-spasmodic, anti-inflammatory, analgesic, anti-diabetic, and anti- Tumor activities, while it is also known to enhance immune function, promote skin repair, stop bleeding and enhance blood circulation. Various compounds have been isolated from the plant, including loureirin A, loureirin B, loureirin C, cochinchinenin, socotrin-4'-ol, 4',7-dihydroxyflavan, 4-methylcholest-7-ene-3-ol, ethylparaben, resveratrol, and hydroxyphenol. The present review summarizes current knowledge concerning the botany, phytochemistry, pharmacological effects, toxicology studies and clinical applications of this resinous medicine as derived from D. cochinchinenesis.
AB - "Dragon's blood" is the name given to a deep red resin obtained from a variety of plant sources. The resin extracted from stems of Dracaena cochinchinensis is one such source of "dragon's blood". It has a reputation for facilitating blood circulation and dispersing blood stasis. In traditional Chinese medicine, this resinous medicine is commonly prescribed to invigorate blood circulation for the treatment of traumatic injuries, blood stasis and pain. Modern pharmacological studies have found that this resinous medicine has anti-bacterial, anti-spasmodic, anti-inflammatory, analgesic, anti-diabetic, and anti- Tumor activities, while it is also known to enhance immune function, promote skin repair, stop bleeding and enhance blood circulation. Various compounds have been isolated from the plant, including loureirin A, loureirin B, loureirin C, cochinchinenin, socotrin-4'-ol, 4',7-dihydroxyflavan, 4-methylcholest-7-ene-3-ol, ethylparaben, resveratrol, and hydroxyphenol. The present review summarizes current knowledge concerning the botany, phytochemistry, pharmacological effects, toxicology studies and clinical applications of this resinous medicine as derived from D. cochinchinenesis.
KW - Botanical source
KW - Clinical application
KW - Dracaena cochinchinenesis
KW - Dragon's blood
KW - Pharmacological activity
KW - Phytochemistry
UR - http://www.scopus.com/inward/record.url?scp=84904806764&partnerID=8YFLogxK
U2 - 10.3390/molecules190710650
DO - 10.3390/molecules190710650
M3 - Review article
C2 - 25054444
AN - SCOPUS:84904806764
SN - 1420-3049
VL - 19
SP - 10650
EP - 10669
JO - Molecules
JF - Molecules
IS - 7
ER -
