A systematic review of the botanical, phytochemical and pharmacological profile of dracaena cochinchinensis, a plant source of the ethnomedicine dragon's blood

Jia Yi Fan*, Tao YI, Chui Mei Sze-To, Lin Zhu, Wan Ling Peng, Ya Zhou Zhang, Zhongzhen ZHAO, Hubiao CHEN

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

50 Citations (Scopus)

Abstract

"Dragon's blood" is the name given to a deep red resin obtained from a variety of plant sources. The resin extracted from stems of Dracaena cochinchinensis is one such source of "dragon's blood". It has a reputation for facilitating blood circulation and dispersing blood stasis. In traditional Chinese medicine, this resinous medicine is commonly prescribed to invigorate blood circulation for the treatment of traumatic injuries, blood stasis and pain. Modern pharmacological studies have found that this resinous medicine has anti-bacterial, anti-spasmodic, anti-inflammatory, analgesic, anti-diabetic, and anti- Tumor activities, while it is also known to enhance immune function, promote skin repair, stop bleeding and enhance blood circulation. Various compounds have been isolated from the plant, including loureirin A, loureirin B, loureirin C, cochinchinenin, socotrin-4'-ol, 4',7-dihydroxyflavan, 4-methylcholest-7-ene-3-ol, ethylparaben, resveratrol, and hydroxyphenol. The present review summarizes current knowledge concerning the botany, phytochemistry, pharmacological effects, toxicology studies and clinical applications of this resinous medicine as derived from D. cochinchinenesis.

Original languageEnglish
Pages (from-to)10650-10669
Number of pages20
JournalMolecules
Volume19
Issue number7
DOIs
Publication statusPublished - Jul 2014

Scopus Subject Areas

  • Analytical Chemistry
  • Chemistry (miscellaneous)
  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry

User-Defined Keywords

  • Botanical source
  • Clinical application
  • Dracaena cochinchinenesis
  • Dragon's blood
  • Pharmacological activity
  • Phytochemistry

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