A strategy for simultaneously realizing the cubic-to-hexagonal phase transition and controlling the small size of NaYF4:Yb 3+,Er3+ nanocrystals for in vitro cell imaging

Zhen Ling Wang; Jianhua Hao; Helen L.W. Chan; Wing Tak Wong; Ka Leung Wong

doi:10.1002/smll.201102703

A strategy for simultaneously realizing the cubic-to-hexagonal phase transition and controlling the small size of NaYF₄:Yb ³⁺,Er³⁺ nanocrystals for in vitro cell imaging

Zhen Ling Wang, Jianhua Hao^*, Helen L.W. Chan, Wing Tak Wong, Ka Leung Wong

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

86 Citations (Scopus)

Abstract

Hexagonal-phase NaYF₄:Yb³⁺,Er³⁺ up-conversion nanocrystals (UCNCs) are synthesized by a combination of refluxing and hydrothermal treatment. This strategy leads to only a slight increase in particle size, from 4.5 to ca. 10 nm, during the cubic-to-hexagonal phase transition. The hexagonal UCNCs can be internalized by HeLa cells and exhibit visible emission in the cells under near-infrared excitation.

Original language	English
Pages (from-to)	1863-1868
Number of pages	6
Journal	Small
Volume	8
Issue number	12
DOIs	https://doi.org/10.1002/smll.201102703
Publication status	Published - 25 Jun 2012

User-Defined Keywords

biosensors
fluorescent probes
imaging
lanthanide nanocrystals
phase transitions

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10.1002/smll.201102703

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abstract = "Hexagonal-phase NaYF4:Yb3+,Er3+ up-conversion nanocrystals (UCNCs) are synthesized by a combination of refluxing and hydrothermal treatment. This strategy leads to only a slight increase in particle size, from 4.5 to ca. 10 nm, during the cubic-to-hexagonal phase transition. The hexagonal UCNCs can be internalized by HeLa cells and exhibit visible emission in the cells under near-infrared excitation.",

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AU - Wang, Zhen Ling

AU - Hao, Jianhua

AU - Chan, Helen L.W.

AU - Wong, Wing Tak

AU - Wong, Ka Leung

PY - 2012/6/25

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N2 - Hexagonal-phase NaYF4:Yb3+,Er3+ up-conversion nanocrystals (UCNCs) are synthesized by a combination of refluxing and hydrothermal treatment. This strategy leads to only a slight increase in particle size, from 4.5 to ca. 10 nm, during the cubic-to-hexagonal phase transition. The hexagonal UCNCs can be internalized by HeLa cells and exhibit visible emission in the cells under near-infrared excitation.

AB - Hexagonal-phase NaYF4:Yb3+,Er3+ up-conversion nanocrystals (UCNCs) are synthesized by a combination of refluxing and hydrothermal treatment. This strategy leads to only a slight increase in particle size, from 4.5 to ca. 10 nm, during the cubic-to-hexagonal phase transition. The hexagonal UCNCs can be internalized by HeLa cells and exhibit visible emission in the cells under near-infrared excitation.

KW - biosensors

KW - fluorescent probes

KW - imaging

KW - lanthanide nanocrystals

KW - phase transitions

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ER -

A strategy for simultaneously realizing the cubic-to-hexagonal phase transition and controlling the small size of NaYF₄:Yb ³⁺,Er³⁺ nanocrystals for in vitro cell imaging

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