@article{a16e0c4e57e54d8d800bacfcce8c8710,
title = "A specific and bioactive polysaccharide marker for Cordyceps",
abstract = "Cordyceps is one of the most expensive and widely used functional foods. But the authenticity is still a concern due to the lack of appropriate markers. By targeting polysaccharides, this study aimed to develop a specific, and bioactive marker for Cordyceps. Firstly, the results of screening tests of 250 samples by examining both genetic markers and polysaccharide profile showed that a unique polysaccharide fraction (named CCP) was particular to the caterpillar parts. Its potential as a marker was further demonstrated by its ability to induce NO and cytokine production in RAW 264.7 cells. CCP was characterized to be an α-1,4-glucan with a branch at C-6 by the conventional structure analyzing and de novo oligosaccharides sequencing. The content of CCP was closely correlated to the traditional classification criteria. Generally, CCP was a marker that simultaneously enables qualitative and quantitative analysis of Cordyceps.",
keywords = "Authentication, Cordyceps, Immune activity, Marker, Polysaccharide",
author = "Lifeng Li and But, {Grace Wing Chiu} and Quanwei Zhang and Man Liu and Chen, {Miao Miao} and Xin Wen and Wu, {Hoi Yan} and Huiyuan Cheng and Puno, {Pema Tenzin} and Zhang, {Ji Xia} and Fung, {Hau Yee} and Bai, {Su Ping} and Wong, {Tin Long} and Zhongzhen Zhao and Hui Cao and Tsim, {Karl Wah Keung} and Shaw, {Pang Chui} and Han, {Quan Bin} and Sun, {Han Dong}",
note = "Funding Information: This work was funded and supported by HKSAR Innovation and Technology Fund (ITF), Tier 3, ITS/311/09 , General Research Fund ( 12100615 , 22100014 , 12100818 ), UGC Research Matching Grant Scheme ( 2019-1-10 , 2019-1-14 , 2019-2-06 ), Health Medical Research Fund (11122531, 14150521, 17182681), National Natural Science Foundation of China ( 81473341 ), the Science and Technology Project of Shenzhen ( JCYJ20160531193812867 ), the Key-Area Research and Development Program of Guangdong Province ( 2020B1111110007 ), Hong Kong Baptist University (RC-Start-up Grants, MPCF-001-2016/2017 , RC-IRMS/14-15/06 , FRG2/17-18/060 and FRG2/16-17/002 ), and Vincent & Lily Woo Foundation . Publisher Copyright: {\textcopyright} 2021 Elsevier Ltd",
year = "2021",
month = oct,
day = "1",
doi = "10.1016/j.carbpol.2021.118343",
language = "English",
volume = "269",
journal = "Carbohydrate Polymers",
issn = "0144-8617",
publisher = "Elsevier Ltd.",
}