A sandwich-type surface-enhanced Raman scattering sensor using dual aptamers and gold nanoparticles for the detection of tumor extracellular vesicles

Min Hou; Dinggeng He; Hongchang Bu; Huizhen Wang; Jin Huang; Jinqing Gu; Ri Wu; Hung Wing Li; Xiaoxiao He; Kemin Wang

doi:10.1039/d0an01385d

A sandwich-type surface-enhanced Raman scattering sensor using dual aptamers and gold nanoparticles for the detection of tumor extracellular vesicles

Min Hou
, Dinggeng He^*
, Hongchang Bu
, Huizhen Wang
, Jin Huang
, Jinqing Gu
, Ri Wu
, Hung Wing Li
, Xiaoxiao He^*
, Kemin Wang^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

20 Citations (Scopus)

Abstract

A sandwich-type surface-enhanced Raman scattering (SERS) sensor using dual aptamers and gold-enhanced Raman signal probes has been successfully constructed for the detection of tumor-derived extracellular vesicles. The simple and sensitive sensor has the capability to detect tumor extracellular vesicles in 10-fold diluted human serum samples.

Original language	English
Pages (from-to)	6232-6236
Number of pages	5
Journal	Analyst
Volume	145
Issue number	19
DOIs	https://doi.org/10.1039/d0an01385d
Publication status	Published - 7 Oct 2020

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10.1039/d0an01385d

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title = "A sandwich-type surface-enhanced Raman scattering sensor using dual aptamers and gold nanoparticles for the detection of tumor extracellular vesicles",

abstract = "A sandwich-type surface-enhanced Raman scattering (SERS) sensor using dual aptamers and gold-enhanced Raman signal probes has been successfully constructed for the detection of tumor-derived extracellular vesicles. The simple and sensitive sensor has the capability to detect tumor extracellular vesicles in 10-fold diluted human serum samples.",

author = "Min Hou and Dinggeng He and Hongchang Bu and Huizhen Wang and Jin Huang and Jinqing Gu and Ri Wu and Li, \{Hung Wing\} and Xiaoxiao He and Kemin Wang",

note = "This work was supported by the Project of Natural Science Foundation of China (21775036, 21675046, 21735002 and 21874035), the Research Foundation of Education Bureau of Hunan Province (18B027), the Hunan Provincial Natural Science Foundation (2018JJ2033), the Research Grant Council of Hong Kong (HKBU12308416 and C2012-15G), and the research committee of Hong Kong Baptist University (FRG2/ 15-16/028). Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",

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doi = "10.1039/d0an01385d",

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T1 - A sandwich-type surface-enhanced Raman scattering sensor using dual aptamers and gold nanoparticles for the detection of tumor extracellular vesicles

AU - Hou, Min

AU - He, Dinggeng

AU - Bu, Hongchang

AU - Wang, Huizhen

AU - Huang, Jin

AU - Gu, Jinqing

AU - Wu, Ri

AU - Li, Hung Wing

AU - He, Xiaoxiao

AU - Wang, Kemin

N1 - This work was supported by the Project of Natural Science Foundation of China (21775036, 21675046, 21735002 and 21874035), the Research Foundation of Education Bureau of Hunan Province (18B027), the Hunan Provincial Natural Science Foundation (2018JJ2033), the Research Grant Council of Hong Kong (HKBU12308416 and C2012-15G), and the research committee of Hong Kong Baptist University (FRG2/ 15-16/028). Publisher Copyright: © The Royal Society of Chemistry.

PY - 2020/10/7

Y1 - 2020/10/7

N2 - A sandwich-type surface-enhanced Raman scattering (SERS) sensor using dual aptamers and gold-enhanced Raman signal probes has been successfully constructed for the detection of tumor-derived extracellular vesicles. The simple and sensitive sensor has the capability to detect tumor extracellular vesicles in 10-fold diluted human serum samples.

AB - A sandwich-type surface-enhanced Raman scattering (SERS) sensor using dual aptamers and gold-enhanced Raman signal probes has been successfully constructed for the detection of tumor-derived extracellular vesicles. The simple and sensitive sensor has the capability to detect tumor extracellular vesicles in 10-fold diluted human serum samples.

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UR - https://pubs.rsc.org/en/content/articlelanding/2020/an/d0an01385d

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SN - 0003-2654

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EP - 6236

JO - Analyst

JF - Analyst

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ER -

A sandwich-type surface-enhanced Raman scattering sensor using dual aptamers and gold nanoparticles for the detection of tumor extracellular vesicles

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