A ratiometric and non-enzymatic luminescence assay for uric acid: Differential quenching of lanthanide excited states by anti-oxidants

Robert A. Poole; Filip Kielar; Siobhan L. Richardson; Philip A. Stenson; David Parker

doi:10.1039/b611259e

A ratiometric and non-enzymatic luminescence assay for uric acid: Differential quenching of lanthanide excited states by anti-oxidants

Robert A. Poole
, Filip Kielar
, Siobhan L. Richardson
, Philip A. Stenson
, David Parker^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

116 Citations (Scopus)

Abstract

The excited states of Tb and Eu complexes of a common macrocyclic ligand are quenched preferentially by electron transfer from the urate anion, allowing the creation of a new assay to measure uric acid in biological fluids.

Original language	English
Pages (from-to)	4084-4086
Number of pages	3
Journal	Chemical Communications
Issue number	39
DOIs	https://doi.org/10.1039/b611259e
Publication status	Published - 18 Sept 2006

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10.1039/b611259e

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@article{8ae29ae20f4544d3b06aaf3d90860cb9,

title = "A ratiometric and non-enzymatic luminescence assay for uric acid: Differential quenching of lanthanide excited states by anti-oxidants",

abstract = "The excited states of Tb and Eu complexes of a common macrocyclic ligand are quenched preferentially by electron transfer from the urate anion, allowing the creation of a new assay to measure uric acid in biological fluids.",

author = "Poole, \{Robert A.\} and Filip Kielar and Richardson, \{Siobhan L.\} and Stenson, \{Philip A.\} and David Parker",

note = "We thank EPSRC, Harrogate LEA and the Royal Society for support. Publisher copyright: {\textcopyright} The Royal Society of Chemistry 2006",

year = "2006",

month = sep,

day = "18",

doi = "10.1039/b611259e",

language = "English",

pages = "4084--4086",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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T1 - A ratiometric and non-enzymatic luminescence assay for uric acid

T2 - Differential quenching of lanthanide excited states by anti-oxidants

AU - Poole, Robert A.

AU - Kielar, Filip

AU - Richardson, Siobhan L.

AU - Stenson, Philip A.

AU - Parker, David

PY - 2006/9/18

Y1 - 2006/9/18

N2 - The excited states of Tb and Eu complexes of a common macrocyclic ligand are quenched preferentially by electron transfer from the urate anion, allowing the creation of a new assay to measure uric acid in biological fluids.

AB - The excited states of Tb and Eu complexes of a common macrocyclic ligand are quenched preferentially by electron transfer from the urate anion, allowing the creation of a new assay to measure uric acid in biological fluids.

UR - https://doi.org/10.1039/B616002F

UR - https://www.scopus.com/pages/publications/33749516680

U2 - 10.1039/b611259e

DO - 10.1039/b611259e

M3 - Journal article

AN - SCOPUS:33749516680

SN - 1359-7345

SP - 4084

EP - 4086

JO - Chemical Communications

JF - Chemical Communications

IS - 39

ER -

A ratiometric and non-enzymatic luminescence assay for uric acid: Differential quenching of lanthanide excited states by anti-oxidants

Abstract

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